A New Scoring System to Predict the Efficacyof Steroid Therapy for Patients With Active Myocarditis

Early and Long-Term Mortality of the Clinical Subtypes of Myocarditis.

“…14,15 Steroid therapy is not indicated for patients with acute common and acute fulminant myocarditis, 16 but a few patients with acute fulminant myocarditis did receive steroid therapy at the clinical stage of multiple organ failure. A significant number of patients with chronic myocarditis were treated by steroid hormones, but we could not estimate the efficacy of this therapy for chronic myocarditis because we have no comparable control.…”

Th1/Th2 Balance Alteration in the Clinical Course of a Patient With Acute Viral Myocarditis.

“…[2][3][4] Cytokines are being recognized as important factors in the pathogenesis and pathophysiology of myocarditis; elevated levels of circulating cytokines have been reported in patients with acute viral myocarditis, 5 and enhanced expression of cytokine genes has been reported in animal models of myocarditis. [6][7][8] Distinct cytokine profiles are clearly associated with the clinical processes of some infectious and immunological diseases and are determined to some extent by 2 functional subsets of T helper (Th) cells, designated as Th1 and Th2.…”

A Fatal Case of Acute Myocardial Infarction following the Improvement of Influenza A(H1N1)pdm2009-related Acute Myocarditis

“…Although corticosteroid administration is tolerated in severe cases according to the guidelines for myocarditis (19), some authors do not recommend its use (20). Meanwhile, some case reports have demonstrated the effectiveness of high-dose intravenous immunoglobulin for acute myocarditis, promoting an antiviral effect and suppressing the inflammatory cytokine expression (21).…”