A New Rehabilitative Mechanism in Primary Motor Cortex After Peripheral Trauma

Fischmeister, Florian Ph. S.; Amini, Ahmad; Matt, Eva; Reinecke, Raphael; Schmidhammer, Robert; Beisteiner, Roland

doi:10.3389/fneur.2020.00125

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…In another line of evidence, several studies have demonstrated that TBPI is capable of promoting structural and functional modifications in the sensory (S1) and motor (M1) primary cortices contralateral and ipsilateral to the affected side ( Mano et al, 1995 ; Malessy et al, 1998 ; Beaulieu et al, 2006 ; Anastakis et al, 2008 ; Taylor et al, 2009 ; Davis et al, 2011 ; Jaggi and Singh, 2011 ; Yoshikawa et al, 2012 ; Liu et al, 2013 ; Fraiman et al, 2016 ; Lu et al, 2016 ; Amini et al, 2018 ; Torres et al, 2018 ; Fischmeister et al, 2020 ). Liu et al (2013) observed changes in interhemispheric connectivity between motor areas, while Fraiman et al (2016) observed reduced functional connectivity in the representation of the trunk and upper limbs bilaterally in M1, suggesting that TBPI might result in alterations of motor control beyond the affected limb.…”

Section: Introductionmentioning

confidence: 99%

Kinematic Changes in the Uninjured Limb After a Traumatic Brachial Plexus Injury

Souza¹,

Lustosa²,

Silva³

et al. 2021

Front. Hum. Neurosci.

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Background: Traumatic brachial plexus injury (TBPI) typically causes sensory, motor and autonomic deficits of the affected upper limb. Recent studies have suggested that a unilateral TBPI can also affect the cortical representations associated to the uninjured limb.Objective: To investigate the kinematic features of the uninjured upper limb in participants with TBPI.Methods: Eleven participants with unilateral TBPI and twelve healthy controls matched in gender, age and anthropometric characteristics were recruited. Kinematic parameters collected from the index finger marker were measured while participants performed a free-endpoint whole-body reaching task and a cup-to-mouth task with the uninjured upper limb in a standing position.Results: For the whole-body reaching task, lower time to peak velocity (p = 0.01), lower peak of velocity (p = 0.003), greater movement duration (p = 0.04) and shorter trajectory length (p = 0.01) were observed in the TBPI group compared to the control group. For the cup-to-mouth task, only a lower time to peak velocity was found for the TBPI group compared to the control group (p = 0.02). Interestingly, no differences between groups were observed for the finger endpoint height parameter in either of the tasks. Taken together, these results suggest that TBPI leads to a higher cost for motor planning when it comes to movements of the uninjured limb as compared to healthy participants. This cost is even higher in a task with a greater postural balance challenge.Conclusion: This study expands the current knowledge on bilateral sensorimotor alterations after unilateral TBPI and should guide rehabilitation after a peripheral injury.

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