For about ten years we have studied radio-frequency as a means of transmitting pulses for heart stimulation from an external source.l*p The most immediate and simplest solution appeared to be the epicardial application of a passive receiver, leading the stimulus to the heart by means of two electrodes. The electrical pulses, in the form of radio-frequency wave trains, were produced by an external tran~mitter.~*~ With this system, we attempted to resolve the problem of breakage of the wire electrodes used in most pacemakers at that time. A total of 38 patients were treated in this manner.This system was abandoned because of the electrophysiological factors that quickly produced fibrosis formation around the pacing electrodes, thus causing their electrical insulation (FIGURE 1 ) . However, the good results obtained with catheter electrodesSl0 prompted us to connect one of these catheters, of the bipolar type, to a radio-frequency receiver of the type previously used, and to implant this unit subcutaneously in the thoracic wall (FIGURE 2). An external transmitter with an annular antenna (FIGURE 3) was placed upon the receiver but outside the thorax.11-13 The transmitter power supply was furnished by rechargeable nickel-cadmium batteries, charged every five days.Catheter use has the notable advantage that thoracotomy is not necessary, and trauma is minimized. Moreover, the following properties of the first system were retained: (1) the ability to change the stimulus energy and to stop the stimulation whenever necessary; (2) the ability to change the cardiac frequency;(3) the ability to modify or replace the pulse transmitter, without a new surgical operation (FIGURE 4 ) . The characteristics of this radiopacemaker, which we have named model RFlZ/C, compared with those of our other models, are reported in TABLE 1.To date, 46 pacemakers of this model have been implanted, since October, 1966. The first 33 were implanted with the United States Catheter & Instrument Co. catheter 5651, which was the only one available at that time in Italy. Although we were aware that this type of catheter was designed by its manufacturer for temporary pacing, we were encouraged to use it for long-term stimulation after our own successful experience and that of others with it. However, we noticed that after a period of time varying from two to 21 months, the woven Dacron insulator between the coaxial conductors, of which the catheter is formed, tended in several cases to absorb organic fluids. This led to a gradual short circuit of the catheter, making the stimulation ineffective.In the meantime, the Medtronic catheters for long-term stimulation became available, and we substituted them for the old catheters in the patients who showed signs of short circuiting. In addition, we encountered one case of receiver failure; two cases of transmitter failure, one of which was due to the batteries; and one case of catheter displacement that could not be overcome with an increase 846