Abstract:Conduit artery endothelial function is most commonly assessed via measurement of flow mediated dilation (FMD) evoked by a transient post‐limb occlusion increase in shear stress [reactive hyperemia (RH)]. A limitation of RH‐FMD is the uncontrolled nature of the RH shear stress stimulus which produces RH‐FMD response variability that is independent of conduit artery endothelial function. The purpose of this study was to develop a protocol to create a uniform, targeted, and transient (40 second) shear stress stim… Show more
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