A new prenylated isoflavone from <i>Derris scandens</i> Benth

Babu, T. Hari; Tiwari, Ashok Kumar; Rao, V. Rama Subba; Ali, Amtul Z.; Rao, J. Madhusudana; Babu, K. Suresh

doi:10.1080/10286020.2010.486378

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…An unrelated study on the same species (cited as Psoralea corylifolia) reports bavarigenin (34) as a constituent of dried ripened fruits. 59 Only 4 examples of O-prenylated isoavones are recorded among the compounds discussed in this section (35,56,57,62). The rst of these, 7-O-prenylbiochanin A (35), was known previously as a synthetic product, 60 but has now been obtained from the root bark of Dalbergia sissoo.…”

Section: Isoflavonesmentioning

confidence: 99%

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Isoflavonoids of the Leguminosae

Veitch

2013

Nat. Prod. Rep.

114

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This account describes 275 new isoflavonoids published between 2008 and 2011 as constituents of the Leguminosae, commenting on their source, identification, biological activity, synthesis, and ecological or chemosystematic significance. Applications of hyphenated analytical techniques to the characterisation of Leguminosae isoflavonoids are also reviewed, together with advances in biosynthetic studies. A checklist of new compounds by species is given, and 226 references are cited.

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Section: Isoflavonesmentioning

confidence: 99%

“…61 Hexane extracts of the whole plant of Derris scandens contain numerous 6,8-diprenylated derivatives of genistein and its methyl ethers, of which scandinone A (36) is a new example. 62 The structure of the linear pyranoisoavone erythraddison A (37) is notable for the unusual hydroxymethyl substituent at C-8 of the A-ring.…”

Section: Isoflavonesmentioning

confidence: 99%

Isoflavonoids of the Leguminosae

Veitch

2013

Nat. Prod. Rep.

114

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“…Its root can be used as an insecticide, diuretics and elixirs [2]. Moreover, several properties of this plant were reported in academic journal such as it showed the inhibitory effect of natural killer cell (NK cell) on HIV-infected patients [3], inhibited the activity of -glucosidase for antidiabetic therapeutics [4,5], antimigration of cancer cells [6]. Its anti-inflammatory property is interesting in this research because it was found to be the most active traditional Thai medicine to reduce inflammation [7].…”

Section: List Of Figuresmentioning

confidence: 99%

Method development for determination of genistein in jewel vine Derris scandens by electrochemical method

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In this work, the in-house screen-printed electrochemical sensor consisted of three-electrode system was developed for genistein determination. A silver/silver chloride (Ag/AgCl) reference electrode, a carbon counter electrode and a carbon working electrode were prepared onto a 0.3 mm-thick plastic substrate by screen-printing of conductive ink through blocking stencil on a woven mesh. The dimension of the sensor 2.5×1.0 cm was received. Only 50 µL of sample solution was required on this device for the determination of genistein concentration by square wave voltammetry. The oxidation peak of genistein appeared with good response in acidic media at a potential of 0.6 V. Moreover, the signal was enhanced by mixing modifying material, cobalt(II) phthalocyanine and graphene, into the conductive carbon ink before screen-printing on a plastic substrate. Under optimized conditions, the linear range was found to be 2.5-150 µM and the detection limit was 1.5 µM for cobalt(II) phthalocyanine modified electrochemical sensor. For graphene modified electrochemical sensor, the linear range was found to be 1-200 µM and the detection limit was 1.0 µM. This proposed method was applied to determine genistein in jewel vine (Derris scandens), a Thai herbal medicine with anti-inflammatory activity, with satisfying results.

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