A new pregnane glycoside fromMarsdenia royleias potential antioxidant and antidyslipidemic agents

Abstract

A new pregnane glycoside roylenine (1) was isolated from the CHCl(3)-EtOH (4:1) extract of Marsdenia roylei. Its structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (6) were evaluated for their antioxidant and antidyslipidemic activities.

Two novel steroidal derivatives from chloroform-soluble extract of Hoya longifolia

“…Plants of this family have been traditionally used for their anti-inflammatory, anti-tumours (Chopra et al 1956;Ahmad, Usmaghani, et al 1983, 1988Ahmad, Noorwala, et al 1993;Masoodi et al 2008;Mahmood et al 2010), immunostimulant (Pan et al 2003(Pan et al , 2013, antidiabetic (Noor et al 2013), anti-oxidant, antimicrobial, anti-complementary, antiepileptic and antineoplastic activities (Piacente et al 1998;Sethi et al 2008Sethi et al , 2012Sethi et al , 2013MacLeod et al 1997). In the search of these novel compounds, various species of the genus Hoya have been examined chemically and a number of biologically active steroids and their glycosides have been isolated (Mahmood et al 2012;Dembitsky et al 2004).…”