“…In addition, the MspI polymorphism of int22h-1, which is 737 bp away from the XbaI polymorphism site, had a heterozygosity rate of 49.5%, and allelic frequencies were 0.61 and 0.39, respectively, for the (+) and (-) alleles (allele +/-= 0.61/0.39 ± 0.0335, 95%CI) in this study. These results are similar to those of Bowen et al (2000), where the heterozygosity rate was 0.46, and allelic frequencies were 0.65 and 0.35, respectively, for the (+) and (-) alleles in 85 male hemophilia A patients in South Wales. This information suggested that a slightly higher informative rate was obtained in the Korean population.…”