A New Oxygenation Index for Reflecting Intrapulmonary Shunting in Patients Undergoing Open-Heart Surgery

Prognostic value of extravascular lung water index in critically ill children with acute respiratory failure

“…Various indexes of oxygen exchange are used to guide mechanical ventilatory support [23] and are used also as prognostic indicators, although their reliability is not universally accepted [24]. At present there are no studies on EVLWi as prognostic indicator in pediatrics.…”

Can pulse oximetric saturation (SpO2)/fraction of inspired oxygen (FiO2) ratio surrogate PaO2/ FiO2 ratio in diagnosing acute respiratory failure?

“…PaO 2 /FiO 2 remains a very important factor to assess the respiratory well being of a patient and was first described by Mohamad El-Khatib et al in one of their studies as an index to compare arterial oxygenation at different levels of FiO 2 . [7] Since then, it has been commonly used to assess respiratory status as well as response to different therapies, whether the therapy is an increase in FiO 2 or changes in mechanical ventilation settings. Moreover, Pao 2 /Fio 2 has been considered as the differentiating factor between establishing a diagnosis for acute lung injury (PaO 2 /FiO 2 <300) (ALI) or a diagnosis for ARDS (PaO 2 /FiO 2 <200).…”

Relationship between the alveolar-arterial oxygen gradient and PaO2/FiO2—Introducing peep into the model

“…This index was established in a sample of patients in the postoperative period of heart surgery, and now appears to be of some usefulness in the pediatric setting----though it has not been extended to adults. 16 The calculation of Grad(A-a)O 2 allows us to assess the ventilation-perfusion imbalance. Accordingly, we have used it to determine whether PaFi can be improved by means of a formula containing PEEP in explaining the diffusion alterations.…”