Golden camellia, a group of herbal materials belonging to the Theaceae family, was widely distributed in Asian countries, particularly Vietnam and southern China. Numerous pharmacological effects of various golden camellia species have been reported in reputable databases such as PubMed and Google Scholar. These effects included anti-tumor, lipid-lowering, anxiolytic, antidepressant, neuroprotective, antioxidant, antibacterial, and anti-inflammatory properties. Furthermore, toxicity studies on golden camellia species have demonstrated their safety for use. Our systematic review provides a comprehensive understanding of the pharmacological effects and safety of various golden camellia species, aiming to provide reliable evidence for the clinical use of this herbal material.