A new nutrient polypeptide-Fe and its antioxidant ability

Liu, Anjun; Wang, Lixia; Ma, Yanhong; Jing-bin, Liu; Zhang, Guorong

doi:10.1080/09637480903061220

Cited by 2 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, most studies on fortifi ed food have focused on amino acid-metal chelates or metal salts, whereas only a few reports have focused on peptide-metal chelates. With higher absorption effi ciency and physiological eff ects, iron supplements that incorporate active peptides are of increasing interest (10).…”

Section: Introductionmentioning

confidence: 99%

Preparation, Identification and Antioxidant Properties of Black-Bone Silky Fowl (Gallus gallus domesticus Brisson) Oligopeptide-Chelated Ferrous Iron

Pan¹,

Song²,

et al. 2016

Food Technol. Biotechnol.

View full text Add to dashboard Cite

Approximately 700 million people suff er from iron deficiency of diff erent degrees, many of whom are women, children and the elderly (1). In developing countries, the situation is worse, 97 % of deaths caused by IDA occur in low-and middle-income countries (2 SummaryBlack-bone silky fowl iron(II)-oligopeptide chelate was synthesized from iron(II) solution and the black-bone silky fowl oligopeptide, which was extracted from the muscle protein of black-bone silky fowl (Gallus gallus domesticus Brisson). Orthogonal array analysis was used to determine the optimal conditions for the iron(II)-oligopeptide chelate preparation. Ultraviolet-visible (UV-Vis) spectroscopy, electron microscopy, and Fourier transform infrared (FTIR) spectroscopy were used to identify the structure of iron(II)-oligopeptide chelate. 2-Diphenyl-1-picrylhydrazyl (DPPH) and superoxide radical scavenging assays were performed to compare the antioxidant abilities of the black-bone silky fowl oligopeptide and iron(II)-oligopeptide chelate. The optimal conditions for iron(II)-oligopeptide chelate preparation were 4 % of the black-bone silky fowl oligopeptide and a ratio of the black --bone silky fowl oligopeptide to FeCl 2 ·4H 2 O of 5:1 at pH=4. Under these conditions, the chelation rate was (84.9±0.2) % (p<0.05), and the chelation yield was (40.3±0.1) % (p<0.05). The structures detected with UV-Vis spectroscopy, electron microscopy and FTIR spectra changed signifi cantly aft er chelation, suggesting that Fe(II) ions formed coordinate bonds with carboxylate (-RCOO¯) and amino (-NH 2 ) groups in the oligopeptides, confi rming that this is a new oligopeptide-iron chelate. The iron(II)-oligopeptide chelate had stronger scavenging activity towards DPPH and superoxide radicals than did the black-bone silky fowl oligopeptide.

show abstract

Section: Introductionmentioning

confidence: 99%

Preparation, Identification and Antioxidant Properties of Black-Bone Silky Fowl (Gallus gallus domesticus Brisson) Oligopeptide-Chelated Ferrous Iron

Pan¹,

Song²,

et al. 2016

Food Technol. Biotechnol.

View full text Add to dashboard Cite

show abstract

Treatments for Iron Deficiency (ID): Prospective Organic Iron Fortification

Wan

Ni³

et al. 2019

CPD

View full text Add to dashboard Cite

Iron deficiency, one of the most common nutritional deficient disorders, frequently affects infants, adolescents and pregnant women and impairs growth, development and immune responses. Iron deficiency may also be secondary to gastrointestinal conditions such as gastrectomy and inflammatory bowel disease, as well as cancer and chronic uremia. Iron supplementation is the most commonly selected treatment option for iron deficiency. This review summarizes the iron compounds currently recommended for the iron fortification of foods and for clinical use. Additionally, this review discusses and compares the important aspects of high-quality iron compounds/products and classes of compounds that enhance iron bioavailability. The development of efficient iron fortification methods remains the most cost-effective and long-term approach to the treatment of iron deficiency or related anemia. To date, no orally administered options for iron fortification can sufficiently replace the parenteral administration of iron supplements, which includes the intramuscular injection of iron-dextran to neonatal piglets and intravenous injection of iron supplements to patients with gastrointestinal disorders. Iron bioavailability may be enhanced by encouraging customers to ingest iron-enriched foods together with dietary sources of vitamin C, folic acid and/or oligosaccharides.

show abstract

A new nutrient polypeptide-Fe and its antioxidant ability

Cited by 2 publications

References 17 publications

Preparation, Identification and Antioxidant Properties of Black-Bone Silky Fowl (Gallus gallus domesticus Brisson) Oligopeptide-Chelated Ferrous Iron

Preparation, Identification and Antioxidant Properties of Black-Bone Silky Fowl (Gallus gallus domesticus Brisson) Oligopeptide-Chelated Ferrous Iron

Treatments for Iron Deficiency (ID): Prospective Organic Iron Fortification

Contact Info

Product

Resources

About