A new model for the explanation of the saturation buildup in the transverse HGMS-configuration

Maaß, W.; Duschl, Markus; Hoffmann, H.; Friedlaender, F.

doi:10.1007/bf00617832

Cited by 14 publications

(2 citation statements)

References 2 publications

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“…This force acts against the tangential component of the hydrodynamic drag force that tends to push the particles out of the deposit. No analytic expression for this static frictional coefficient has been developed, but for some particular cases experimental values have been calculated (26).…”

Section: Modeling and Simulationmentioning

confidence: 99%

Simulating the Embolization of Blood Vessels Using Magnetic Microparticles and Acupuncture Needle in a Magnetic Field

Rotariu

Iacob

Strachan

et al. 2008

Biotechnol Progress

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Computer models were developed to simulate the capture and subsequent deposition of magnetic microparticles (MMPs) in a blood vessel adjacent to a ferromagnetic wire (e.g., acupuncture needle) magnetized by a uniform external magnetic field. Process parameter conditions were obtained to enable optimal capture of MMPs into the deposit. It was found that the maximum capture distance of the MMPs was within 0.5-2.0 mm when the particles were superparamagnetic and had large size (>1.0 microm) and relative large flow rates (2.5-5.0 cm/s) as in a healthy artery. It was also found that the deposits were asymmetrical and that their size was between 1.0 and 2.0 mm. For the case of lower flow rates as can be found in a tumor (<1.0 mm/s) and using small magnetite particles (0.25-2.0 microm) the maximum capture distance was larger, ranging between approximately 0.5 and 6.4 mm, depending on the blood flow rate, the radius of wire, and particle clustering. The range of embolization (deposition) in this later case was between 0.5 and 5.9 mm. The potential of this technique to generate MMPs deposits to embolize blood vessels inhibiting the blood supply and thus facilitating necrosis of tumors located deep within the patient (3-7 cm) is discussed.

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Section: Modeling and Simulationmentioning

confidence: 99%

Simulating the Embolization of Blood Vessels Using Magnetic Microparticles and Acupuncture Needle in a Magnetic Field

Rotariu

Iacob

Strachan

et al. 2008

Biotechnol Progress

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show abstract

“…The transversal configuration has a static model [11] considering that besides the magnetic and drag forces a "phenomenological" static friction force acting on a particle belonging to the last layer of the buildup.…”

Section: Introductionmentioning

confidence: 99%

The effect of suspension concentration on the buildup evolution in a HGMF-axial magnetic filter

Murariu¹,

Rezlescu²,

Rotariu³

et al. 1998

Eur. Phys. J. AP

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In this work the influence of solid particles concentration from suspension on the buildup evolution for a single wire from a magnetic filter working in axial configuration is presented. The buildup differential equations are solved and the surface contour of the buildup at different moments is obtained. It is evidenced the existence of a suspension concentration for which the radial deposit extension is maximum.

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Particle accumulation on a single wire in transverse HGMS configuration

et al. 1987

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A new model for the explanation of the saturation buildup in the transverse HGMS-configuration

Cited by 14 publications

References 2 publications

Simulating the Embolization of Blood Vessels Using Magnetic Microparticles and Acupuncture Needle in a Magnetic Field

Simulating the Embolization of Blood Vessels Using Magnetic Microparticles and Acupuncture Needle in a Magnetic Field

The effect of suspension concentration on the buildup evolution in a HGMF-axial magnetic filter

Particle accumulation on a single wire in transverse HGMS configuration

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