A New MMPI-Derived Indicator of Liability to Develop Schizophrenia: Evidence from the New York High-Risk Project

Bolinskey, P. Kevin; Gottesman, Irving I.; Nichols, David S.; Shapiro, Barbara Maminski; Roberts, Simone A.; Adamo, Ulla Hilldoff; Erlenmeyer‐Kimling, L.

doi:10.1177/107319110100800202

Cited by 34 publications

(52 citation statements)

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We examined the psychometric properties and construct validity for a Minnesota Multiphasic Personality Inventory-2 Schizophrenia Proneness (SzP ) scale (Bolinskey et al, 2001) and provided normative statistics. Premorbid participants were offspring of parents with schizophreniarelated illness (SRI), with comparison groups of offspring of parents with major affective disorders and offspring of normals.

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confidence: 99%

The Schizophrenia Proneness (SzP) scale: An MMPI‐2 measure of schizophrenia liability

2003

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We examined the psychometric properties and construct validity for a Minnesota Multiphasic Personality Inventory-2 Schizophrenia Proneness (SzP) scale (Bolinskey et al., 2001) and provided normative statistics. Premorbid participants were offspring of parents with schizophrenia-related illness (SRI), with comparison groups of offspring of parents with major affective disorders and offspring of normals. Postmorbid participants were twins affected with SRI; their unaffected relatives served as a comparison group. Results suggest that an SzP T score of 65 or above is an effective indicator of personality processes associated with increased liability to developing SRI.

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The Schizophrenia Proneness (SzP) scale: An MMPI‐2 measure of schizophrenia liability

2003

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“…Several existing MMPI scales have been shown to aid the prediction of schizophrenia-spectrum outcomes. [28][29][30] Our interest, however, was not in replicating these successes, but in identifying an a priori set of MMPI items, selected purely on the basis of their similarity to EASE content domains, and examining the predictive properties of this analogue self-disorder scale. Our criterion would be to select any MMPI item statement that, if spontaneously presented as a complaint by the subject in an EASE interview, would motivate the EASE interviewer to explore it in-depth as a potential token of SD.…”

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confidence: 99%

Premorbid self‐disorders and lifetime diagnosis in the schizophrenia spectrum: a prospective high‐risk study

Parnas

Carter

Nordgaard

2014

Early Intervention Psych

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Aim: The notion of a disordered self as a core disturbance of schizophrenia was proposed in many foundational texts. Recent studies, spurred by the development of the Examination of Anomalous Self-Experience (EASE), seem to indicate that selfdisorders are a specific manifestation of schizophrenia vulnerability. Follow-up studies of help-seeking, prodromal and first-admission patients have demonstrated the utility of self-disorders for predicting later schizophrenia-spectrum disturbance. We wished to extend these findings by gauging the predictive value of self-disorders in a premorbid, non-clinical population at high risk for schizophrenia. Methods:Children from the Copenhagen High-Risk Project with highgenetic risk for schizophrenia (N = 212) were assessed premorbidly (average age = 15), and diagnostically re-evaluated after 10 and 25 years. Since the EASE was not available at the time of premorbid assessment, we hypothesized that a proxy scale drawn from the Minnesota Multiphasic Personality Inventory (MMPI) could distinguish those who later developed a schizophrenia-spectrum disorder (N = 68) from those who remained healthy (N = 64). The Self-Disorder Scale comprised 32 items whose content suggested an aspect of selfdisorder as measured by the EASE.Results: Premorbid Self-Disorder Scale scores significantly predicted lifetime schizophrenia-spectrum diagnosis in the high-risk cohort. Although there was considerable item overlap between the new scale and an existing MMPI scale (psychoticism), the overlap did not account for the Self-Disorder Scale's predictive efficacy. Conclusion:The results support the notion of self-disorders as a core vulnerability feature in schizophrenia, detectable premorbidly in those developing later schizophreniaspectrum disorders.

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“…Scale 10 evaluates social style including introversion/extroversion, desire for interaction and interpersonal skills. 30 …”

Section: Scale 9 Measures Hypomania (Ma)mentioning

confidence: 99%

“…30 The original purpose of the MMPI was to assist in diagnosis of psychological disorders; however, it has also been found to be effective in personality and behavioral description. 31 The use of code types in interpretation is well researched and common in clinical practice.…”

Section: The Minnesota Multiphasic Personality Inventory (Mmpi)mentioning

confidence: 99%

Sex steroids and personality traits in the middle luteal phase of healthy normally menstruating young professional women

Avgoustinaki¹,

Mitsopoulou²,

Chlouverakis³

et al. 2012

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.10, F(1,57)=6.23, p=0.016). We were unable to find any association between the circulating androgens and scores on the masculinity-femininity scale (Mf). We were also unable to document any association between the weak adrenal androgens DHEA and DHEA-S and depression in contrast to several published reports. (c) Our data suggest a marginally significant association between progesterone and scores on the 7-Pt (obsessive/compulsive/psychasthenia) scale (r=0.27, p<0.05). However, only 7% of the 7-Pt variance was explained by progesterone (r 2 =0.071, F(1,50)=3.81, p=0.057). cONcluSIONS: We have found that total testosterone was associated with the paranoia score, the metabolic product of activated androgens, 3alpha-diolG, to social introversion and, finally, progesterone to obsessive-compulsive behavior.

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A New MMPI-Derived Indicator of Liability to Develop Schizophrenia: Evidence from the New York High-Risk Project

Cited by 34 publications

References 41 publications

The Schizophrenia Proneness (SzP) scale: An MMPI‐2 measure of schizophrenia liability

The Schizophrenia Proneness (SzP) scale: An MMPI‐2 measure of schizophrenia liability

Premorbid self‐disorders and lifetime diagnosis in the schizophrenia spectrum: a prospective high‐risk study

Sex steroids and personality traits in the middle luteal phase of healthy normally menstruating young professional women

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