A new mixed pyrazole-diamine/Ni(II) complex, Crystal structure, physicochemical, thermal and antibacterial investigation

Abstract

The new mixed complex {[2Ni(L1) 2 .2Ni(L1)(L2)].2(NO 3 ) 4 .2H 2 O} was obtained from a mixture, under aerobic conditions, of a solution of Ni(NO 3 ) 2 ,6H 2 O and the two diamine pyrazolic ligands L1, N1-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)propane-1,2-diamine, and L2, N2-((3,5-dimethyl-1H-pyrazol-1-yl)-methyl)propane-1,2-diamine. Obtained in very good yield, this complex was identified and characterized by FT-IR, EDX, ultraviolet-visible spectroscopies and single-crystal X-ray diffraction (XRD). The structural peculiarity is that two isomeric forms of molecules C 18 H 36 N 8 Ni have co-crystallized with H 2 O and NO 3 molecular units. The triclinic structure of P1 symmetry is stabilized by the numerous hydrogen bonds that occur in the crystal lattice. The thermal behavior of this Ni(II) complex was studied in an open atmosphere via TG/DTG. The L1, L2 ligands and the Ni(II) complex were evaluated for their antibacterial activity against a series of Gram-negative and Grampositive bacteria.

Aminothiazole-Linked Metal Chelates: Synthesis, Density Functional Theory, and Antimicrobial Studies with Antioxidant Correlations

“…The metal complexes gained a lipophilic feature as a result of the chelation, which helps their absorption through the lipid membrane of microbes . The solubilization, contact, permeability, and length of the link between the metal and ligand lipid layers of bacterium membranes are all elements to consider …”

New Catalysts Based on Carboxylate Sn(IV) Complexes Used in the Oxidation Reaction of 3,5-Di-Tert-Butylcatechol to 3,5- Di-Tert-Butyl-O-Benzoquinone

“…In the literature, we noted studies concerning the synthesis of biomimetic oxidation catalysts to reproduce catecholase activity [24][25][26][27][28][29][30]. Most of the results described use catalysts with the aim of mimicking the metallic active site environment of the catecholase enzyme and also understanding the catalytic properties for activating molecular oxygen.…”

Synthesis, Characterization, DFT, and Thermogravimetric Analysis of Neutral Co(II)/Pyrazole Complex, Catalytic Activity toward Catecholase and Phenoxazinone Oxidation

“…In a flask fitted with a magnetic stirrer, one equivalent of 1-hydroxymethyl-3,5dimethylpyrazole (5 g) in 40 mL of acetonitrile was mixed with one equivalent of 5chloropyridin-2-amine in 20 mL of acetonitrile (Scheme 1). The reaction was stirred at room temperature for 120 h, and then the mixture was dried over MgSO 4 , filtered and concentrated with a rotavapor and purified by CH 2 Cl 2 /H 2 O extraction [21][22][23]. tals 2023, 13, x FOR PEER REVIEW 3 of impurities and then left to evaporate at room temperature.…”