A new method for topology design of electromagnetic antennas in hyperthermia therapy

Amad, Alan A. S.; Loula, Abimael F. D.; Novotny, Antônio André

doi:10.1016/j.apm.2016.10.010

Cited by 12 publications

(6 citation statements)

References 28 publications

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“…Assim foi calculado o número de elementos para que a condição fosse estritamente menor do que um, gerando uma malha com pouco mais de 400mil elementos finitos triangulares iguais, através da função poimesh do Ma-tLab. Foram usadas 168 antenas pontuais fixas em torno do corpo B e dentro do domínio Ω, utilizou-se β = 0.5, θ Γ = 36 o C e frequência de 300MHz, escolhida por gerar melhores resultados e estar na faixa de frequências usadas na literatura [1,8,9]. Nos dois experimentos realizados considera-se que o corpo B está cercado porágua deio- [1].…”

Section: Experimentosunclassified

“…Foram usadas 168 antenas pontuais fixas em torno do corpo B e dentro do domínio Ω, utilizou-se β = 0.5, θ Γ = 36 o C e frequência de 300MHz, escolhida por gerar melhores resultados e estar na faixa de frequências usadas na literatura [1,8,9]. Nos dois experimentos realizados considera-se que o corpo B está cercado porágua deio- [1]. O maior valor de corrente foi da ordem de 0.4A, considerando os três casos.…”

Section: Experimentosunclassified

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Projeto de Antenas Pontuais para Tratamento por Hipertermia

Mattoso¹,

Novotny²

2020

Proceeding Series of the Brazilian Society of Computational and Applied Mathematics

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Resumo. Este trabalho tem como objetivo projetar antenas pontuais para serem utilizadas em tratamentos por Hipertermia. Objetiva-se calcular o valorótimo de corrente que deve passar em cada antena para que um alvo, formado por células cancerosa, seja aquecido de forma seletiva. Um funcional que mede a diferença entre as temperatura alvo e a calculada numericamenteé minimizado em relaçãoà corrente, utilizando conceito de Derivada Topológica. Propõe-se a solução do problema através apenas da derivada de primeira ordem, buscando-se de forma iterativa a soluçãoótima. Palavras-chave. Hipertermia, Equação de Bioheat, Equação de Helmholtz, Derivada Topológica.

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Section: Experimentosunclassified

Projeto de Antenas Pontuais para Tratamento por Hipertermia

Mattoso¹,

Novotny²

2020

Proceeding Series of the Brazilian Society of Computational and Applied Mathematics

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“…Thus, a robust and computationally efficient algorithm is needed to address the complexity of such systems. Various techniques have been reported in the literature for SAR optimization in EM hyperthermia systems such time reversal [ 50 ], fixed-time topology [ 51 ], inverse multiphysics strategy [ 52 ], genetic algorithms in [ 13 , 14 , 53 ], eigenvalue based optimization in [ 12 ], projection algorithm in [ 54 ], and particle swarm optimization in [ 55 ]. We devise an optimization technique based on the genetic algorithm to reduce any possible hotspots.…”

Section: The Proposed Energy Localization Techniquesmentioning

confidence: 99%

Enhanced Energy Localization in Hyperthermia Treatment Based on Hybrid Electromagnetic and Ultrasonic System: Proof of Concept with Numerical Simulations

Nizam-Uddin

Elshafiey

2017

BioMed Research International

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This paper proposes a hybrid hyperthermia treatment system, utilizing two noninvasive modalities for treating brain tumors. The proposed system depends on focusing electromagnetic (EM) and ultrasound (US) energies. The EM hyperthermia subsystem enhances energy localization by incorporating a multichannel wideband setting and coherent-phased-array technique. A genetic algorithm based optimization tool is developed to enhance the specific absorption rate (SAR) distribution by reducing hotspots and maximizing energy deposition at tumor regions. The treatment performance is also enhanced by augmenting an ultrasonic subsystem to allow focused energy deposition into deep tumors. The therapeutic faculty of ultrasonic energy is assessed by examining the control of mechanical alignment of transducer array elements. A time reversal (TR) approach is then investigated to address challenges in energy focus in both subsystems. Simulation results of the synergetic effect of both modalities assuming a simplified model of human head phantom demonstrate the feasibility of the proposed hybrid technique as a noninvasive tool for thermal treatment of brain tumors.

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“…Moreover, the heat of a large volume of fabrics is also a challenging task by using these waves. 15 In general, these waves have proven to be effective against deposition of energy in the affected part of skin, or the affected tissue volume (for example in the muscle, veins, organs extra) resulted in the excitation of tumour cells and hence killing of these cells due to high temperature. For ideal treatment, these waves should show minimum leakage of energy outside of the impacted area so that no killing of normal and healthy cells occurs.…”

Section: Introductionmentioning

confidence: 99%