A new method for the preparation of substituted 5,6,7,8-tetrahydro-4H-I-benzopyran and 4H-pyrans by vilsmeier -haack reagent.

Venugopal, M.; Umarani, R.; Perumal, Paramasivan T.; Rajadurai, S.

doi:10.1016/s0040-4039(00)79732-2

Cited by 25 publications

(7 citation statements)

References 11 publications

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“…The Vilsmeier-Haack reagent (POCl 3 /DMF) is a versatile reagent capable of performing various synthetic transformations, for example, formylation, 10 cyclohaloaddition, 11 cyclization, 12 and ring annulations. 13 It is an efficient, eco-nomical, and mild reagent for the formylation of reactive aromatic and heteroaromatic substrates 14 and provides a powerful synthetic tool for the construction of heterocyclic compounds.…”

Section: Figure 1 Pyridocarbazole Alkaloidsmentioning

confidence: 99%

Synthesis of Novel Pyridocarbazoles Analogues of Ellipticine

Meesala

Ezzat

Mordi

et al. 2014

Synlett

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Section: Figure 1 Pyridocarbazole Alkaloidsmentioning

confidence: 99%

Synthesis of Novel Pyridocarbazoles Analogues of Ellipticine

Meesala

Ezzat

Mordi

et al. 2014

Synlett

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“…It has been proved that the Vilsmeier‐Haack reagent is a multipurpose reagent which is capable of performing many synthetic transformations . It is applied in formylation , cyclohaloaddition , cyclization and ring annulations . We have synthesized the novel 1,8‐naphthyridine derivatives using the reaction of 2‐substituted vinamidinium salts with 2,6‐diaminopyridine.…”

Section: Introductionmentioning

confidence: 99%

A Novel Synthesis of New 1,8‐Naphthyridine Derivatives Using the Reaction of Vinamidinium Salts With 2,6‐Diaminopyridine

Jahromi

Mehranpour

2016

Journal of Heterocyclic Chem

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“…The Vilsmeier-Haack reagent has been proved to be averstile reagent capable of executing a large variety of synthetic transformations [16]. It finds applications in formylation [17], cyclohaloaddition [18], cyclisation [19] and ring annulations [20].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of new derivatives of 2-chloro-3-formyl-1,8-naphthyridine

Saleh

Ayoub

2014

Eur. J. Chem.

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A simple and regioselective synthesis of 2-chloro-3-formyl-1,8-naphthyridine, through Vilsmeier-Haack cyclization of N-(pyridin-2-yl)acetamide has been reported. The reaction of 2-chloro-3-formyl-1,8-naphthyridine is also investigated and new series of 1,8-naphthyridine derivatives such as 3-chloro-4-(2-chloro-1,8-naphthyridine-3-yl)-1-(phenylamino)azetidin-2one, 3-chloro-4-(2-chloro-1,8-naphthyridin-3yl)-1-((4-nitrophenyl) amino)-azetidin-2-one and 3-chloro-4-(2-chloro-1,8-naphthyridine-3-yl)-1-((2,4-dinitrophenyl) amino)-azetidin-2one have been prepared. The formyl group in the 1,8-naphthyridine is subjected to further transformation into alkoxy carbonyl (NIS-K2CO3/alcohol) to afford 3-alkoxy carbonyl-1,8naphthyridine and new hetero cyclic compounds such as oxadiazolo, thiadiazolo-thion and triazolo-thion have been prepared. The reaction between 2-chloro-3-formyl-1,8naphthyridine and sodium sulphide in DMF produced 2-mercapto-3-formyl-1,8naphthyridine. Some of the prepared compounds were found to have good biological activity against Staphylococcus aureus and Staphylococcus epidermidis.Triazol Thiadizol Azetidine Oxadiazol Naphthyridine Vilsmeier-Haack

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A new method for the preparation of substituted 5,6,7,8-tetrahydro-4H-I-benzopyran and 4H-pyrans by vilsmeier -haack reagent.

Cited by 25 publications

References 11 publications

Synthesis of Novel Pyridocarbazoles Analogues of Ellipticine

Synthesis of Novel Pyridocarbazoles Analogues of Ellipticine

A Novel Synthesis of New 1,8‐Naphthyridine Derivatives Using the Reaction of Vinamidinium Salts With 2,6‐Diaminopyridine

Synthesis of new derivatives of 2-chloro-3-formyl-1,8-naphthyridine

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