“…They were requested to fill a questionnaire concerning various symptoms, and their Kupperman's menopausal indices (Kupperman et al 1959; Abe et al 1975) were calculated. Then, the patients were given an intravenous injection of 20 mg of conjugated estrogen (Premarin) and the menopausal indices were calculated again on the thrid or the fourth day after injection.…”