A new method based on electrospray ionisation ion mobility spectrometry (ESI-IMS) for simultaneous determination of caffeine and theophylline

Jafari, Mohammad T.; Rezaei, Behzad; Javaheri, Majid

doi:10.1016/j.foodchem.2010.12.054

Cited by 91 publications

(38 citation statements)

References 27 publications

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“…The most popular include chromatographic techniques such as high-performance liquid chromatography (HPLC), high-performance thin layer chromatography (HPTLC), or capillary electrophoresis with ultraviolet (UV) or mass spectrometry (MS) detection. They allow the determination of caffeine as a single compound in herbal products and energy drinks or its separation from other alkaloids in chocolate, tea, coffee, urine, or serum (Abourashed and Mossa 2004;Tokusoglu and Kemal 2002;Jafari et al 2011;Perrone et al 2008;Peri-Okonny et al 2005;Zhao and Lunte 1997). Caffeine can be separated from polyphenols in tea and coffee (Hadad et al 2012;Samanidou et al 2012;Poerner and Bragagnolo 2013) or from other drugs in pharmaceutical preparations (Gámiz-Gracia and Luque de Castro 1997; Zen and Ting 1997;Sultan et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Caffeine and Water-Soluble Vitamins in Energy Drinks by HPLC with Photodiode Array and Fluorescence Detection

Gliszczyńska‐Świgło

Rybicka

2014

Food Anal. Methods

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The high-performance liquid chromatography (HPLC) method with photodiode array (PDA) and fluorescence (FL) detection for the simultaneous separation and determination of caffeine and water-soluble vitamins is described. The method is relatively rapid: 13 compounds can be analyzed within 30 min: caffeine; ascorbic acid (vitamin C); thiamine (vitamin B 1 ); riboflavin 5-phosphate (FMN, flavin mononucleotide) and riboflavin (vitamin B 2 ); nicotinic acid and nicotinamide (vitamin B 3 ); pantothenic acid (vitamin B 5 ); pyridoxal, pyridoxamine, and pyridoxine (vitamin B 6 ); folic acid (vitamin B 9 ); and cyanocobalamin (vitamin B 12 ). This HPLC method is designated for quantification of caffeine and water-soluble vitamins in liquid and tablet energy drinks as well as for determination of vitamins in vitamin supplements. The method was validated in terms of linearity, limit of detection (LOD) and quantification (LOQ), accuracy, and instrument precision. The LODs determined using HPLC-PDA ranged from 13 to 121 ng mL −1 and using HPLC-FL were between 8 and 61 ng mL −1. Intra-and interday instrument precisions for liquid energy drink, expressed as relative standard deviation (RSD), were less than 1.87 and 1.73 %, respectively, and less than 1.44 and 1.83 %, respectively, for tablet energy drink. The method could be useful in the quantitative analysis of caffeine and of water-soluble vitamins in energy drinks and vitamin supplements.

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Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Caffeine and Water-Soluble Vitamins in Energy Drinks by HPLC with Photodiode Array and Fluorescence Detection

Gliszczyńska‐Świgło

Rybicka

2014

Food Anal. Methods

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“…From the optical techniques UV with LOD of 5 Â 10 À4 M (FernandezMaestre & Hill, 2009), FT-infrared with LOD of 2 Â 10 À4 M (Ito et al, 2008), FT-Raman with LOD of 9 Â 10 À5 M (Koleva, Kolev, Tsalev, & Spiteller, 2008) and NMR with LOD of 7 Â 10 À3 M (del Campo, Berregi, Caracena, & Zuriarrain, 2010) spectrometry were usually employed for caffeine determination. The separation methods such as capillary electrophoresis (Zhao & Lunte, 1997), thinlayer chromatography (Sullivan & Sherma, 2005), gas chromatography (Jafari, Rezaei, & Javaheri, 2011) and liquid chromatography (Tzanavaras & Themelis, 2007;Zougagh, Rios, & Valcarcel, 2005) were used for the analysis of mixtures containing caffeine and other drugs or metabolites.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric determination of caffeine in beverage samples on bare boron-doped diamond electrode

et al. 2012

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“…From the optical techniques UV (Fernandez-Maestre, Hill, 2009), FT-infrared (Ito et al, 2008), FT-Raman (Koleva et al, 2008) and NMR (Armenta et al, 2005) spectrometry were usually employed for caffeine determination. The separation methods such as capillary electrophoresis (Zhao, Lunte, 1997), thinlayer chromatography (Sullivan, Sherma, 2005), gas chromatography (Jafari et al, 2011) and liquid chromatography (Tzanavaras, Themelis, 2007) were used for the analysis of mixtures containing caffeine and other drugs or metabolites. However, these techniques are mostly very expensive and long time is required for some procedures as derivatization, extraction and purifi cation (Goyal et al, 2011) therefore, the development of reliable, low-cost, rapid, simple and accurate method for caffeine determination in various foodstuffs, pharmaceutical formulations and biological fl uids is needed.…”

Section: Introductionmentioning

confidence: 99%

Utilization of electrochemical methods in determination of trace elements in beverages

Svítková¹,

Machková²,

Šatkovská³

et al. 2012

Acta Chimica Slovaca

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Electrochemical methods have many inherent advantages such as simplicity, low cost and amenability to miniaturization. A new, sensitive and selective electrochemical method for the caffeine determination using boron doped diamond electrode was developed. It was found by cyclic voltammetry that caffeine provided highly reproducible and well-defi ned irreversible oxidation peak, at very positive potential of +1.55 V vs. Ag/AgCl electrode. The effect of pH and scan rate on the voltammetric response of caffeine oxidation were studied to select the optimum experimental conditions. Linear response of peak current on the concentration in the range from 4 × 10 -7 to 2.5 × 10 -5 mol L -1, good repeatability (RSD of 2.1 %) and the detection limit of 1.5 × 10 -7 mol L -1 without any chemical modifi cations and electrochemical surface pretreatment were observed by differential pulse voltammetry in 0.4 mol L -1 perchloric acid. The effect of possible interfering compounds appeared to be negligible which evidently proved very good selectivity. The proposed method was successfully applied for the caffeine determination in commercially available beverage samples, with results in a close statistical agreement to these declared by manufacturer.

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A new method based on electrospray ionisation ion mobility spectrometry (ESI-IMS) for simultaneous determination of caffeine and theophylline

Cited by 91 publications

References 27 publications

Simultaneous Determination of Caffeine and Water-Soluble Vitamins in Energy Drinks by HPLC with Photodiode Array and Fluorescence Detection

Simultaneous Determination of Caffeine and Water-Soluble Vitamins in Energy Drinks by HPLC with Photodiode Array and Fluorescence Detection

Voltammetric determination of caffeine in beverage samples on bare boron-doped diamond electrode

Utilization of electrochemical methods in determination of trace elements in beverages

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