A New Member of the Inverted Cucurbit[<i>n</i>]uril Family

Wang, Xinxin; Chen, Kai; Shen, Fang‐Fang; Hua, Zi-Yi; Qiu, Sheng-Chao; Zhang, Yun‐Qian; Cong, Hang; Liu, Qingyun; Tao, Zhu; Xiao, Xin

doi:10.1002/chem.201704069

Cited by 13 publications

(3 citation statements)

References 35 publications

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“…Cucurbit[ n ]urils (Q[ n ]), which are pumpkin-shaped macrocyclic host molecules, have garnered substantial awareness since they can tightly bind to different biological molecules in the solid state and aqueous solution (Kim et al, 2000 ; Day et al, 2002 ; Li et al, 2016 ; Chen et al, 2017a ; Gao et al, 2017a , b ; Wang et al, 2017 ). Several examples of supramolecular assemblies of Q[ n ] and certain BAs have been reported (Masson et al, 2009 ; Chen et al, 2017b ).…”

Section: Introductionmentioning

confidence: 99%

Study on the Binding Interaction of the α,α′,δ,δ′-Tetramethylcucurbit[6]uril With Biogenic Amines in Solution and the Solid State

et al. 2018

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1H NMR spectroscopy and MALDI-TOF mass spectrometry were utilized to examine the binding interaction of α,α′,δ,δ′-tetramethylcucurbit[6]uril (TMeQ[6]) and six biogenic amines (spermine, spermidine, 2-phenethylamine, tyramine, histamine, and tryptamine). Their 1H NMR spectra both at pD = 7 and pD = 3 revealed that four biogenic amines (spermine, spermidine, 2-phenethylamine, and histamine) can fit in the TMeQ[6] cavity, respectively, and other biogenic amines were located outside of the TMeQ[6] portal. In addition, a solid-state evaluation with single-crystal X-ray diffraction analysis showed the binding interaction of spermine, spermidine, 2-phenethylamine, and tyramine with TMeQ[6].

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Section: Introductionmentioning

confidence: 99%

Study on the Binding Interaction of the α,α′,δ,δ′-Tetramethylcucurbit[6]uril With Biogenic Amines in Solution and the Solid State

et al. 2018

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“…[14][15][16][17][18][19] For example, activity changes could be found both in CB [8]induced FGG-cap-9 dimer [18] (compared with FGG-cap-9 monomer) and CB [8]-induced split-luciferase complementation [19] (compared with split fragments). [14][15][16][17][18][19] For example, activity changes could be found both in CB [8]induced FGG-cap-9 dimer [18] (compared with FGG-cap-9 monomer) and CB [8]-induced split-luciferase complementation [19] (compared with split fragments).…”

Section: Introductionmentioning

confidence: 99%

“…Recently, CB[n]s-based supramolecular assembly has been widely used to tune the functions of proteins. [14][15][16][17][18][19] For example, activity changes could be found both in CB [8]induced FGG-cap-9 dimer [18] (compared with FGG-cap-9 monomer) and CB [8]-induced split-luciferase complementation [19] (compared with split fragments). Other properties could be tuned by CB[n]s-induced protein assembly.…”

Section: Introductionmentioning

confidence: 99%

Cucurbituril As A Versatile Tool to Tune the Functions of Proteins

Hou¹,

Zeng

Gao

et al. 2017

Israel Journal of Chemistry

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Tuning the functions of proteins is a key issue in chemistry and biochemistry. The modification of proteins by chemical or biological methods is proven to be a classical method that allows proteins to achieve multiple functions. Compared with traditional methods, cucurbiturils as a new series of macrocyclic supramolecular hosts have been explored to modify and control protein functions because they could recognize and bind to short aromatic peptide sequences specifically. After guest molecules are incorporated into proteins by chemical and biological methods, CB[n]‐induced supramolecular protein assemblies show distinct functions in catalysis, biosensor and drug delivery. Herein we review the recent progress in the field of functional regulation of proteins with cucurbiturils.

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A Study of the Interaction Between Cucurbit[8]uril and Alkyl‐Substituted 4‐Pyrrolidinopyridinium Salts

Kan

et al. 2018

Chemistry An Asian Journal

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The interaction between cucuribit[8]uril (Q[8]) and as eries of 4-pyrrolidinopyridiniums alts bearing aliphatic substituents at the pyridiniumn itrogen, namely 4-(C 4 H 8 N)C 5 H 5 NRBr,w here R = Et (g1), n-butyl (g2), n-pentyl (g3), n-hexyl (g4), n-octyl (g5), n-dodecyl (g6), has been studied in aqueous solution by 1 HNMR spectroscopy,e lectronic absorption spectroscopy,i sothermal titrationc alorimetry and mass spectrometry.S ingle crystal X-ray diffraction revealed the structure of the host-guest complexes for g1, g2, g3, and g5. In each case, the Q[8] contains two guest molecules in ac entrosymmetric dimer.T he orientation of the guest molecule changes as the alkyl chain increases in length. Interestingly,i nt he solid state, the inclusion complexes identified are different from those observed in solution,a nd furthermore, in the case of g3, Q[8] exhibits two different interactions with the guest.I ns olution,t he length of the alkyl chain plays as ignificant role in determiningt he type of host-guest interaction present.[a] W.Supporting information and the ORCID identification number(s) for the author(s) of this article can be found under: https://doi.

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A New Member of the Inverted Cucurbit[n]uril Family

Cited by 13 publications

References 35 publications

Study on the Binding Interaction of the α,α′,δ,δ′-Tetramethylcucurbit[6]uril With Biogenic Amines in Solution and the Solid State

Study on the Binding Interaction of the α,α′,δ,δ′-Tetramethylcucurbit[6]uril With Biogenic Amines in Solution and the Solid State

Cucurbituril As A Versatile Tool to Tune the Functions of Proteins

A Study of the Interaction Between Cucurbit[8]uril and Alkyl‐Substituted 4‐Pyrrolidinopyridinium Salts

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