A new Mannich base and its transition metal (II) complexes — Synthesis, structural characterization and electrochemical study

Abstract

A new Mannich base, N-(1-morpholinobenzyl) semicarbazide (MBS), formed by the condensation of morpholine, semicarbazide and benzaldehyde, and its Cu(II), Ni(II), Co(II) and Zn(II) complexes have been synthesized. Their structures have been elucidated on the basis of analytical, magnetic, electrical conductivity and spectral study as well as elemental analyses. The complexes exhibit square-planar geometry. The monomeric and non-electrolytic nature of the complexes is evidenced by their magnetic susceptibility and low conductance data. The electrochemical property of the ligand and its complexes in acetonitrile solution was studied by cyclic voltammetry. The X-band ESR spectra of the Cu(II) complex in DMSO at 300 and 77 K were recorded and their salient features are reported.

A New Mannich Base N-[Phenyl(pyrrolidin-1- Yl)methyl]acetamide - Synthesis, Spectral Properties, Antibacterial and Antifungal Studies of Some of Its Metal Complexes

“…The multiplet in the range δ7.39-7.26 ppm is attributed to the protons of the benzene ring. [24] The protons at δ7.39, According to the 13 C NMR spectrum obtained, the carbonyl carbon shows a signal at δ169.62…”

“…The resonance signals at δ141.62, 128.56, 127.99 and 127.68 ppm are assigned to the carbons of the phenyl group at 1, 2&6, 3&5 and 4 positions respectively. The substituted carbon of the aromatic ring can be distinguished by its decreased [24] peak height(δ141.62 ppm). The signals observed at δ49.23 and 23.59 ppm is due to at α, α 1 and at β, β 1 carbons of pyrrolidine ring.…”

Metal Complexes of N-[Morpholine-4-Yl-(4- Nitrophenyl)-Methyl]-Benzamide: Synthesis, Characterization and Evaluation of Pesticidal and Larvicidal Activity

“…The mode of coordination and its" sites were pointed out by comparing the IR spectrum of ligand and its complexes. [28,29,30] IR data concludes that the ligand acts as a bidentate and coordination occurs through O and N atoms to the metal ions. …”

Synthesis, characterization and antibacterial activity of Pyrrolidine based Mannich base ligand and its metal (II) complexes

“…From the survey of existing literature [1][2][3][4][5] , it appears that metal complexes of Mannich bases have played a vital role in the development of coordination chemistry. It is well known from the literature that the compounds containing amide moiety have a strong ability to form metal complexes and exhibit a wide range of biological activities.…”

“…Earlier work reported that some drugs showed increased activity when administered as metal chelates rather than as organic compounds. It is well known from the literature that semicarbazide compounds 5 containing the amide moiety have a strong ability to form metal complexes. Therefore, it was thought worthwhile to synthesise some metal complexes of this type of Mannich base and investigate its bonding characteristics.…”