A new in-vitro blood test for determining thyroid status—the effective thyroxine ratio

Hypervitaminosis A accompanying advanced chronic renal failure.

“…There was no significant difference between mean serum vitamin A in the controls (0-94±0-28 (0 03) iLmol/l (27-75±8-10 (0 8) ,g/100 ml) ) and that in patients with acute renal failure (0-96±0-30 (008) ,umol/l (27-50±8-57 (2)(3)(4) ,ug/ 100 ml) (t=009). In contrast the mean value was high in patients with advanced chronic renal failure (2-13±0-73 (0-07) t±mol/l (60-93±21-0 (2-1) ,g/100 ml) (t= 15-0), and higher in patients undergoing chronic haemodialysis (3-00±0-72 (0-07) pmol/l (85-37±20-49 (2 0) ±g/100 ml) (t=26 2).…”

Studies on the Accuracy of a Quantitative Kit Radioimmunoassay for Free Thyroxine

“…The changes in fT, (Corning) during pregnancy were inconsistent with this pattern (Table 2). There was a 3 40% decrease in the fT, (Corning relative rate) during the second and third trimesters. In contrast, f'T, (Corning modified method) increased during the first trimester and fell slightly but significantly during the second and third trimesters.…”

Understanding Thyroid Disease: Lessons for the Future

“…It should be noted that all measurements of free T4, except that of Jacobs et al (1973), give a percentage of non protein-bound hormone and it is still necessary to know the total concentration to derive the required figure for absolute free hormone concentration. In recent years single tests for free T4 have been introduced-for example, the effective thyroxine ratio (ETR) (Mincey et al, 1971). My own experience of these tests is limited: they appear to give a good if not absolute correlation with more elaborate tests.…”