A new cis-p-coumaroyl flavonol glycoside from the inner barks of Sophora japonica L.

Abstract

A new cis -p -coumaroyl flavonol glycoside from the inner barks of Sophora japonica L.Abstract : Tree barks could be a rich source of novel bioactive compounds, which are not well explored. In this work, the chemical constituent investigation of extractives from the inner barks of Sophora japonica L. (Leguminosae) led to the isolation of a new cis -p -coumaroyl flavonol glycoside, which was elucidated as kaempferol 3-O -(4 ″ -cisp -coumaroyl)-α -rhamnopyranoside ( IV ). The structure of the new compound was established mainly based on extensive spectroscopic techniques. In addition, among the four known phenolics purified in this study, including three flavonol glycosides [rutin ( I ), kaempferol-3-O -(6 ″ -galloyl)-β -glucopyranoside ( II ), and quercitrin ( V )], as well as a phenolic acid [ trans -ferulic acid ( III )], compounds II and III have never been reported in S. japonica previously.

Flavonol profiles of mature leaves allow discriminating Toona sinensis Roem from different north-south geographical origins across China with varied antioxidant activities

“…This compound had been purified from T. sinensis , and the galloylation was confirmed to have a strong influence on its antileukemic activity [ 29 ]. This compound has also been detected in Morus alba [ 41 ], Sophora japonica L. [ 42 ], and Diospyros kaki Thunb. (persimmon) [ 39 ].…”

Chemical Constituents of the Terrestrial Stems of Ephedra sinica and their PPAR-γ Ligand-Binding Activity

“…Thus, the MeOH and EtOH-soluble fractions were passed through column chroma-Chemical Constituents of the Terrestrial Stems of Ephedra sinica and their PPAR-γ Ligand-Binding Activity tography on silica gel and octadecylsilanized (ODS) silica gel producing compounds 1-10. Compounds 1-9 were identified as β-sitosterol (1) [10], 7β-hydroxysitosterol (2) [11], 7α-hydroxysitosterol (3) [11], kaempferol-3-O-rhamnoside (4) [12], kaempferol-3-O-(4″-trans-p-coumaroyl)-rhamnopyranoside (5) [13], kaempferol-3-O-(4″-cis-p-coumaroyl)-rhamnopyranoside (6) [14], herbacetin-7-O-glucopyranoside (7) [6], mahuanin A (8) [15], and ephedrannin A (9) [16], respectively (▶Fig. 1).…”