A new hybrid electro-numerical model of the left ventricle

Kozarski, Maciej; Ferrari, Gianfranco; Zieliński, Krzysztof; Górczyńska, Krystyna; Pałko, Krzysztof Jakub; Tokarz, A.; Darowski, M.

doi:10.1016/j.compbiomed.2008.07.001

Cited by 20 publications

(19 citation statements)

References 12 publications

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“…Among others, the modules sketched in Fig.1 contain a complex of simpler models of systemic and pulmonary circulation, 7-8 models of congenital heart defects 9 and of surgical procedures, 10 interfaces to respiratory models, now under development, models of heart assist devices (LVAD, RVAD, BVAD, IABP, BIV pacing), [11][12][13] models of autonomic controls (in this moment baroreflex and metabolic controls, the second one under development), 8,14 and interfaces for educational use of the platform. 8 The polymorphism of the structure has been achieved through implementation of the concept of hybrid modelling, [15][16][17][18][19] in cooperation with the Nałecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Science. In short, hybrid models permit to merge computational and physical models when and if necessary.…”

Section: Methodsmentioning

confidence: 99%

Circulatory Modelling as a Clinical Decision Support and an Educational Tool

Ferrari¹,

Molfetta²,

Zieliński³

et al. 2015

BMDJ

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Section: Methodsmentioning

confidence: 99%

Circulatory Modelling as a Clinical Decision Support and an Educational Tool

Ferrari¹,

Molfetta²,

Zieliński³

et al. 2015

BMDJ

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“…It was already described in details in [14]. Now, only basic information to describe the model operation will be given.…”

Section: Structure Of the Modelmentioning

confidence: 99%

“…In 2008 we published the results of testing the arterial loading structure effect on some circulatory parameters [15] and presented the above mentioned concept of a hybrid electronumerical circulatory model [14]. Each model of blood circulation, irrespective of its structure and application, is based on a mathematical model in its numerical (computer) shape.…”

Section: Hybrid (Hydro-numerical) Model Of the Circulationmentioning

confidence: 99%

“…In 2008, we published in Computers in Biology and Medicine a new concept of a hybrid electro-numerical model of the left ventricle [14] leading to the creation of a complete hybrid model of a cardio-vascular system. It was built at the Institute of Biocybernetics and Biomedical Engineering (IBIB) of the Polish Academy of Sciences (PAN) -Warsaw, Poland, to be used as a complementary tool in clinical investigations.…”

Section: Introductionmentioning

confidence: 99%

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A new hybrid (hydro-numerical) model of the circulatory system

Darowski¹,

Kozarski²,

Ferrari³

et al. 2013

Bulletin of the Polish Academy of Sciences: Technical Sciences

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Abstract. The paper presents a hybrid (hydro-numerical) circulatory model built to be used as a complementary tool for clinical purposes. It was developed at the Institute of Biocybernetics and Biomedical Engineering -Polish Academy of Sciences (Poland) in co-operation with the Institute of Clinical Physiology -National Council of Research (Italy). Main advantages of the model are: 1) high accuracy and repeatability of parameters setting, characteristic of numerical solutions, 2) maximum flexibility achieved by implementing the largest possible number of the model's elements in the numerical way, 3) ability to test mechanical heart assist devices provided by special computer applications; in the model two physically different signal environments -numerical and hydraulic -are connected by special impedance transformers interfacing physical and numerical parts of the model; 4) eliminating flowmeters, as the voltage controlled flow sources embedded in the system provide information on flows.In vitro tests were performed to evaluate the circulatory model: a) modelling and simulation of physiological and pathological states parameters vs. left ventricular end-systolic elastance (E max l ) and rest volume (V o l ) variations, b) testing the effect of LVAD counterpulsation on circulatory hemodynamics and ventricular energetics; it resulted in the increase of total cardiac output (COLV tot) from pathological value 3.8 to 5.4 l·min −1 , mean aortic pressure mPas from 67.8 to 96.1 mmHg and in the decrease of left atrial pressure mP la from 15.7 to 7.7 mmHg and External Work nEW by 37.5%.The model was verified based on literature data.

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“…The assist device was connected to a hybrid circulatory system model, which is based on a numerical description of the circulation system and includes impedance converters developed at the Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences [10]. These converters transfer the 114 Alicja Siewnicka et al …”

Section: Identification Experimentsmentioning

confidence: 99%

Application of a PExSim for modeling a POLVAD artificial heart and the human circulatory system with left ventricle assistance

Siewnicka

Fajdek

Janiszowski

2010

Polish Journal of Medical Physics and Engineering

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This paper presents a model of the human circulatory system with the possible addition of a parallel assist device, which was developed for the purpose of artificial heart monitoring. Information about an identification experiment of an extracorporeal ventricle assist device POLVAD is included. The modelling methods applied and the corresponding functional blocks in a PExSim package are presented. The results of the simulation for physiological conditions, left ventricle failure and pathological conditions with parallel assistance are included.

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A new hybrid electro-numerical model of the left ventricle

Cited by 20 publications

References 12 publications

Circulatory Modelling as a Clinical Decision Support and an Educational Tool

Circulatory Modelling as a Clinical Decision Support and an Educational Tool

A new hybrid (hydro-numerical) model of the circulatory system

Application of a PExSim for modeling a POLVAD artificial heart and the human circulatory system with left ventricle assistance

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