A New Hope for Liquid Biopsies: Early Detection of Pancreatic Cancer By Means of Protease Activity Detection in Serum Applying a Hierarchical Decision Structure
Abstract:Over the last 6 years, five-year survival rate for pancreatic cancer patients has increased from 6 to 10% after the initial diagnosis, which makes it one of the deadliest cancer types. This disease is known as the “silent killer” because early detection is challenging due to the location of the pancreas in the body and the nonspecific clinical symptoms. The Bossmann group has developed ultrasensitive nanobiosensors for protease/arginase detection comprised of Fe/Fe3O4nanoparticles, cyanine 5.5, and designer pe… Show more
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