Summary. Haemoglobin Lepore was demonstrated in four members of a Turkish family. It was found in the heterozygote state and was associated with erythrocyte morphology similar to that observed in the , thalassaemia trait. The average concentration of haemoglobin Lepore was 8.1% of the total haemoglobin.Structural analysis showed that the Lepore haemoglobin was the LeporeBoston type.