A new framework for interleaved scanning in cardiovascular MR: Application to image‐based respiratory motion correction in coronary MR angiography

Henningsson, Markus; Mens, Giel; Koken, Peter; Smink, Jouke; Botnar, René M.

doi:10.1002/mrm.25149

Cited by 31 publications

(39 citation statements)

References 11 publications

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“…A dynamically interleaved 2D/3D dual-sequence scheme was implemented in a dedicated acquisition framework [ 28 ]. All images were acquired on a 1.5 T Philips Achieva MR system (Philips Healthcare, Best, The Netherlands) using a 5-element cardiac receive coil array.…”

Section: Methodsmentioning

confidence: 99%

Quantitative three-dimensional myocardial perfusion cardiovascular magnetic resonance with accurate two-dimensional arterial input function assessment

Wissmann¹,

Niemann²,

Gotschy³

et al. 2015

Journal of Cardiovascular Magnetic Resonance

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BackgroundQuantification of myocardial perfusion from first-pass cardiovascular magnetic resonance (CMR) images at high contrast agent (CA) dose requires separate acquisition of blood pool and myocardial tissue enhancement. In this study, a dual-sequence approach interleaving 2D imaging of the arterial input function with high-resolution 3D imaging for myocardial perfusion assessment is presented and validated for low and high CA dose.MethodsA dual-sequence approach interleaving 2D imaging of the aortic root and 3D imaging of the whole left ventricle using highly accelerated k-t PCA was implemented. Rest perfusion imaging was performed in ten healthy volunteers after administration of a Gadolinium-based CA at low (0.025 mmol/kg b.w.) and high dose (0.1 mmol/kg b.w.). Arterial input functions extracted from the 2D and 3D images were analysed for both doses. Myocardial contrast-to-noise ratios (CNR) were compared across volunteers and doses. Variations of myocardial perfusion estimates between volunteers and across myocardial territories were studied.ResultsHigh CA dose imaging resulted in strong non-linearity of the arterial input function in the 3D images at peak CA concentration, which was avoided when the input function was derived from the 2D images. Myocardial CNR was significantly increased at high dose compared to low dose, with a 2.6-fold mean CNR gain. Most robust myocardial blood flow estimation was achieved using the arterial input function extracted from the 2D image at high CA dose. In this case, myocardial blood flow estimates varied by 24 % between volunteers and by 20 % between myocardial territories when analysed on a per-volunteer basis.ConclusionInterleaving 2D imaging for arterial input function assessment enables robust quantitative 3D myocardial perfusion imaging at high CA dose.

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Section: Methodsmentioning

confidence: 99%

Quantitative three-dimensional myocardial perfusion cardiovascular magnetic resonance with accurate two-dimensional arterial input function assessment

Wissmann¹,

Niemann²,

Gotschy³

et al. 2015

Journal of Cardiovascular Magnetic Resonance

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“…An MRS sequence was interleaved with a gradient echo imaging sequence using an interleaved scanning framework . The MRS localization and acquisition were omitted, but the water suppression was still performed using the VAPOR sequence with a bandwidth of 200 Hz.…”

Section: Methodsmentioning

confidence: 99%

“…The single voxel sLASER MRS sequence was localized in the occipital cortex, where typically visual functionality is investigated, and was interleaved with a GE‐EPI imaging sequence, as typically used for fMRI . Because the focus of this work is image and spectral quality due to achieved B 0 homogeneity, no visual stimulation was applied and functional analysis was omitted.…”

Section: Methodsmentioning

confidence: 99%

MR spectroscopy using static higher order shimming with dynamic linear terms (HOS‐DLT) for improved water suppression, interleaved MRS‐fMRI, and navigator‐based motion correction at 7T

Boer

Andersen²,

Lind

et al. 2020

Magnetic Resonance in Med

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Purpose: To interleave global and local higher order shimming for single voxel MRS. Single voxel MR spectroscopy requires optimization of the B 0 field homogeneity in the region of the voxel to obtain a narrow linewidth and provide high data quality. However, the optimization of local higher order fields on a localized MRS voxel typically leads to large field offsets outside that volume. This compromises interleaved MR sequence elements that benefit from global field homogeneity such as water suppression, interleaved MRS-fMRI, and MR motion correction. Methods: A shimming algorithm was developed to optimize the MRS voxel homogeneity and the whole brain homogeneity for interleaved sequence elements, using static higher order shims and dynamic linear terms (HOS-DLT). Shimming performance was evaluated using 6 brain regions and 10 subjects. Furthermore, the benefits of HOS-DLT was demonstrated for water suppression, MRS-fMRI, and motion corrected MRS using fat-navigators. Results: The HOS-DLT algorithm was shown to improve the whole brain homogeneity compared to an MRS voxel-based shim, without compromising the MRS voxel homogeneity. Improved water suppression over the brain, reduced image distortions in MRS-fMRI, and improved quality of motion navigators were demonstrated using the HOS-DLT method. Conclusion: HOS-DLT shimming allowed for both local and global field homogeneity, providing excellent MR spectroscopy data quality, as well as good field 1102 | BOER Et al. K E Y W O R D S1 H MR spectroscopy, B 0 shimming, EPI distortions, prospective motion correction, ultra-high field, water suppression

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“…For instance, when the MRI can switch seamlessly between two interleaved sequences [8]. An example for this (e.g.…”

Section: B Requirementsmentioning

confidence: 98%

PET/MR Synchronization by Detection of Switching Gradients

Weissler

Gebhardt

Lerche

et al. 2015

IEEE Trans. Nucl. Sci.

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The full potential of simultaneous Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) acquisition, such as dynamic studies or motion compensation, can only be explored if the data of both modalities is temporally synchronized. As such hybrid imaging systems are commonly realized as custom-made PET inserts for commercially available MRI scanner, a synchronization solution has to be implemented (depending on the vendor of the MRI system). In contrast, we demonstrate a simple method for temporal synchronization, which does not require a connection to the MRI. It uses the normally undesired effect of induced voltages on the PET electronics from switching MRI gradients. The electronic circuit needs very few components and the gradient pick-up coils are made from PCB traces and vias on the PET detector boards. Neither programming the MRI nor any physical connection to the MR scanner is needed, thus avoiding electromagnetic compatibility problems. This method works inherently with most MRI sequences and is a vendor-independent solution. A characterization of the sensors in an MRI scanner showed that the MRI gradients are detected with a precision of s (with the current implementation). Using different trigger thresholds, it is possible to trigger selectively on certain MRI sequences, depending on their gradient slew rate settings. Timings and pulse diagrams of MRI sequences can be recognized from the generated Manuscript

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A new framework for interleaved scanning in cardiovascular MR: Application to image‐based respiratory motion correction in coronary MR angiography

Cited by 31 publications

References 11 publications

Quantitative three-dimensional myocardial perfusion cardiovascular magnetic resonance with accurate two-dimensional arterial input function assessment

Quantitative three-dimensional myocardial perfusion cardiovascular magnetic resonance with accurate two-dimensional arterial input function assessment

MR spectroscopy using static higher order shimming with dynamic linear terms (HOS‐DLT) for improved water suppression, interleaved MRS‐fMRI, and navigator‐based motion correction at 7T

PET/MR Synchronization by Detection of Switching Gradients

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