A new exploration of Dregea volubilis flowers: Focusing on antioxidant and antidiabetic properties

Das, Bhaskar; De, Arnab; Das, Mousumi; Das, Sangita; Samanta, Amalesh

doi:10.1016/j.sajb.2016.12.003

Cited by 30 publications

(31 citation statements)

References 30 publications

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“…At 100 lg/mL, the scavenging rates of WE, EAE and ascorbic acid were 36.81 ± 1.75%, 27.10 ± 0.54% and 72.76 ± 2.38%, respectively. In comparison with other plants of the family Apocynaceae, the DPPH radical scavenging activity of T. jasminoides was higher than that reported for Hunteria umbellata [38], and a little weaker than that of Dregea volubilis [39].…”

Section: Dpph Radical Scavenging Activitycontrasting

confidence: 66%

“…Therefore, removing hydroxyl radicals is quite important for the antioxidant defence in living cell systems. As illustrated in Figure 7 and Table 2 [39], which was a bit lower than that of the EAE of T. jasminoides.…”

Section: Hydroxyl Radical Scavenging Activitymentioning

confidence: 74%

“…The in vitro a-glucosidase inhibitory studies demonstrated that the extracts of T. jasminoides had inhibitory activity. As is shown in [38], and higher than that of Dregea volubilis (3780.09 ± 21.19 vg/mL) [39]. These differences may be ascribed to the nature of the phenolics and flavonoids of the extracts, which were proved to be effective inhibitors of ,-glucosidases [42].…”

Section: A-glucosidase Inhibitory Activitymentioning

confidence: 77%

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Cytotoxic activities against MCF-7 and MDA-MB-231, antioxidant andα-glucosidase inhibitory activities ofTrachelospermum jasminoidesextractsin vitro

Song

Zhang

Gong

et al. 2019

Biotechnology & Biotechnological Equipment

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The present study investigated the cytotoxic activities against MCF-7 and MDA-MB-231 cells, and the potential antioxidant and a-glucosidase inhibitory activities of the extracts of the aerial parts of Trachelospermum jasminoides, a traditional medicinal plant used for the treatment of rheumatic arthralgia in China. In MTT assay and microscopic analysis, the ethyl acetate extract (EAE) of T. jasminoides showed moderate cytotoxic effect against MCF-7 and MDA-MB-231 with IC 50 values of 109.54 ± 2.39 lg/mL and 162.68 ± 9.52 lg/mL, respectively, but the water extract (WE) was inactive against both of them. With gallic acid and rutine as equivalents for determination, the total phenolic and total flavonoid contents in the EAE (54.93 ± 0.32 mg GAE/g and 186.75 ± 4.55 mg RE/ g, respectively) were higher than those of the WE. The antioxidant activities of the EAE and WE, which were evaluated by reducing power assay, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay and hydroxyl radical scavenging assay, may be directly associated with the high contents of phenols and flavonoids in T. jasminoides. The EAE showed higher inhibitory effect in the a-glucosidase inhibition tests with an IC 50 value of 776.81 ± 107.80 lg/mL as compared to the WE with 2607.48 ± 364.31 lg/mL. Furthermore, the antioxidant activity and the inhibitory effects of the fractions against a-glucosidase were concentration-dependent. ARTICLE HISTORY

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Section: Dpph Radical Scavenging Activitycontrasting

confidence: 66%

Section: Hydroxyl Radical Scavenging Activitymentioning

confidence: 74%

Section: A-glucosidase Inhibitory Activitymentioning

confidence: 77%

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Cytotoxic activities against MCF-7 and MDA-MB-231, antioxidant andα-glucosidase inhibitory activities ofTrachelospermum jasminoidesextractsin vitro

Song

Zhang

Gong

et al. 2019

Biotechnology & Biotechnological Equipment

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“…In Traditional Myanmar Medicine, Dregea volubilis, the most used wild species, was used to treat multiple diseases such as Indigestion, dyspepsia, dysentery, diarrhea and insomnia [50]. The functional compounds of the species were identified as a group of Dregeosides which had effective activities such as antibacterial, antioxidant and antidiabetic [51][52][53]. Centella asiatica could improve the symptoms of insomnia and forgetfulness, according to the informants.…”

Section: : Centella Asiaticamentioning

confidence: 99%

The Secret of Health in the Daily Cuisine: the Typical Health Vegetables in the Local Markets in Central Myanmar

Zhang

San³

et al. 2020

Preprint

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BackgroundCentral Myanmar locate in the Indo-Burma Biodiversity hotspot, and Barma people is the main ethnic group which had settled there over thousands years ago. Nevertheless, as the major Myanmar ethnic group, Bamar people were ignored in Ethnobotanical studies. Market surveys are considered a good strategy for the preliminary screening of potential Ethnopharmacological plant resources. In the present study, we focused on the local health knowledge of vegetables of Bamar people in local markets.Materia and methods:In the present study, we surveyed the local markets, then recorded, collected, identified and catalogued the typical vegetables, and document the knowledge of health benefits of the collected vegetables, then analyze the information of vegetables and local knowledge. The observation and interviews were used in field study, and the Ethnobotanical Indexes were used to analyze the local knowledge. We compare the local knowledge we collected with traditional medicine literatures.Results10 Markets and fairs were selected in Mandalay Region, Magway Region, Yangon Region and Nay Pyi Taw Union Territory, and in a total of 277 vegetable stalls or shops were visited. 132 plant taxa were collected and identified. Many of the healthy vegetables were cited as functional food had health benefit by the informants (106 taxa, 80.3%) while others were just regarded as “good for health” (26 taxa, 19.7%). Over half of the taxa were recorded as traditional medicinal plants with health functions in previous studies. The main health function of the vegetables was treating digestion problems.ConclusionThe diversity and use of the health vegetables in central Myanmar were very rich. Some previous Phytochemical and Pharmacological studies on these plants showed that their extracts had effective activities or compounds related to health functions. It should be noted the food safety of the vegetables in future researches.Yu Zhang and Jian-Wen Li contribute equally to the article.

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“…Ethanol extract of D. volubilis flowers has remarkable inhibitory effects on α-glucosidase and α-amylase activities [3]. At both oral doses of 100 and 200 mg/kgP/day during 15 days of treatment, petroleum ether extract of D. volubilis fruits dose dependently normalized blood glucose levels in streptozotocin induced hyperglycemic rats [4]. The chemical constituents of this plant have been then studied and showed to contain a lot of polyhydroxypregnanes and polyhydroxypregnane glycosides [5,6], pentacyclic triterpenes [7], and flavonoids [8].…”

Section: Introductionmentioning

confidence: 99%

Polyhydroxypregnane Glycosides From Dregea Volubilis

Kiệm¹

2020

JST

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A new exploration of Dregea volubilis flowers: Focusing on antioxidant and antidiabetic properties

Cited by 30 publications

References 30 publications

Cytotoxic activities against MCF-7 and MDA-MB-231, antioxidant andα-glucosidase inhibitory activities ofTrachelospermum jasminoidesextractsin vitro

Cytotoxic activities against MCF-7 and MDA-MB-231, antioxidant andα-glucosidase inhibitory activities ofTrachelospermum jasminoidesextractsin vitro

The Secret of Health in the Daily Cuisine: the Typical Health Vegetables in the Local Markets in Central Myanmar

Polyhydroxypregnane Glycosides From Dregea Volubilis

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