A New Entity Following Cardiac Valve Replacement

Merendino, K. Alvin; Manhas, Dev R.

doi:10.1097/00000658-197306000-00008

Cited by 30 publications

(9 citation statements)

References 16 publications

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“…[1][2][3] The mechanism of gallstone formation is thought to be related to continuous latent mechanical hemolysis after surgery. 1,2 However, the results of our previous study 3 showed that gallstones developed relatively early after surgery, i.e., 80.0% of patients developed stones within 6 months, and no patients developed gallstones after 12 months.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] The mechanism of gallstone formation is thought to be related to continuous latent hemolysis mechanically induced by the replacement valve. 1,2 However, the results of our previous study showed that gallstones developed relatively early after surgery (i.e., 80.0% of patients developed stones within 6 months), and our results also suggested that gallstone formation might be more strongly related to acute hemolysis associated with the use of a heart-lung machine. 3 We therefore postulated that gallstone formation might be preventable by taking appropriate measures before or soon after surgery.…”

Section: Introductionmentioning

confidence: 99%

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Prevention of gallstones by ursodeoxycholic acid after cardiac surgery

Azemoto

Saisho

2003

Journal of Gastroenterology

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevention of gallstones by ursodeoxycholic acid after cardiac surgery

Azemoto

Saisho

2003

Journal of Gastroenterology

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“…Intravascular haemolysis is a problem of minor significance in comparison with thrombo-embolic complications, but has nevertheless been reported by several authors (Eyster et al, 1971;Santinga & Kirsh, 1972;Merendino & Manhas, 1973). The problems of haemolysis are greater in patients with aortic valve prosthesis, but also occur after mitral valve replacement.…”

Section: Discussionmentioning

confidence: 99%

Significance of Position and Opening Angle of the Björk-Shiley Tilting Disc Valve in Mitral Surgery

Björk

Böök

Holmgren

1973

Scandinavian Journal of Thoracic and Cardiovascular Surgery

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The opening angle of the Bjork-Shiley mitral prosthesis was increased from 50" to 60" and the prosthesis rotated 180" in the mitral annulus to direct the downward moving part of the disc towards the posterior leaflet base, in an attempt to optimize the pressureflow relationship of the prosthesis. The material for the disc occluder was changed to pyrolytic carbon and the new sewing ring had two flanges.Thirty-one consecutive patients with isolated mitral lesions were studied before and 5-12 months following mitral valve replacement. Prior to operation, 25/31 (81 %) of the patients were in N.Y.H.A. function class 111 or IV, 28/31 (90 %) were in atrial fibrillation, the central circulation was markedly hypokinetic and the left atrial and pulmonary artery pressures were markedly elevated.Early mortality within 1 month of operation was 6 %, while there was no late mortality after an observation period of 12-24 months. Subjective and N.Y.H.A. function class improvement was observed in 22/27 (82 %). Thrombo-embolic complications occurred in 2 patients (7 %). All patients were anticoagulated. Persistent atrial fibrillation was found in 13/27 (48 %). The central haemodynamics were markedly improved with increased stroke volume and cardiac output, decrease in left atrial and pulmonary artery pressures and reduction in both pulmonary and systemic vascular resistance. The pressure-flow relationships of the prostheses were studied and found to be highly satisfactory. A persistent large left atrial u-wave was a common finding.The clinical and haemodynamic results are discussed and the present material is compared with a similar one in which the prosthesis opened at an angle of 50" and was rotated with the large orifice towards the anterior mitral leaflet. The more favourable pressure-flow relationships across the mitral orifice are discussed and it is suggested that the posterior rotation of the prosthesis is themost important factor. In order to achieve this aim, the prosthesis was rotated 180" with the larger downward moving portion of the disc directed towards the posterior mitral leaflet base.The purpose of the present investigation was to study the effect on the central haemodynamics of these changes. the parietal wall. In order to achieve this, the prosthesis was rotated 180" with the larger, downward moving portion of the disc directed towards the posterior mitral leaflet base.Scand J Thor Cardiovasc Surg 7 Scand Cardiovasc J Downloaded from informahealthcare.com by Flinders University of South Australia on 01/08/15For personal use only.

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“…However, a higher incidence of this disease has been seen in patients who underwent heart valve replacement surgeries [15,16].…”

Section: Introductionmentioning

confidence: 99%