A new endocapsular open ring for prevention of anterior and posterior capsule opacification

Abstract

PurposeThe aim of this study is to demonstrate the functionality of a new design of a thick endocapsular open ring for prevention of anterior capsule opacification (ACO) and posterior capsule opacification (PCO).SettingThe Institute of Vision and Optics, University of Crete and University Hospital of Heraklion, Crete, Greece.DesignProspective, interventional pilot study.MethodsFifteen patients (17 eyes) underwent cataract surgery with phacoemulsification. During surgery, a thick endocapsular open ring (peripheral capsule reconstructor) was inserted into the capsular bag, prior to intraocular lens (IOL) implantation. Six different models of IOL were implanted. Postoperatively, the degree of ACO and PCO was evaluated and described as none, mild, moderate, or severe.ResultsThe mean follow-up period was 30±8.06 months (range: 12–36 months). At the last follow-up, mild PCO was observed in only three eyes and mild ACO in three patients. The centration of IOLs was good in all but one eye, which had a tilted IOL.ConclusionThe results of this pilot study suggest that the implantation of a new design of thick endocapsular open ring is feasible and may contribute to the prevention of PCO and ACO after cataract surgery.

Quantitative Evaluation of Human Lens Epithelial Cell Viability and Cytolysis by Distilled Water Ex Vivo

“…Currently, there are two possible preventive directions against lens capsule opaci cation: inhibiting the proliferation, migration, and EMT of LECs, and clearing the LECs as far as possible. The former includes using drugs to inhibit the proliferation, migration, or EMT of LECs 9 , implantation of hydrophobic sharp-edged IOLs 10 or a thick endocapsular open ring to inhibit the migration of LECs to the posterior capsule 11 . However, LECs remain within the capsular bag and the causative reason can't be eliminated 12 .…”