A New Diagnostic Test for Antiglobulin Positive (‘Auto‐Immune’) Haemolytic Anaemia*

Pirofsky, Bernard

doi:10.1111/j.1365-2141.1960.tb06258.x

Cited by 6 publications

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References 9 publications

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“…The calcium 23 APRIL 1982 concentration in the CF strains increased significantly between passages 7 and 14 (P < .0005), after which a plateau was reached (12). When cellular calcium in both groups reached a plateau (passages 14 to 20), the mean calcium concentration was 50 percent greater in CF (0.57 ± 0.02 p,g of calcium per milligram of ash, N = 5) than in control (0.38 + 0.01 ,ug of calcium per milligram of ash, N = 4) strains (P < .0005) (13). These experiments did not enable us to distinguish, as the cells aged, between increased calcium in all or most cells of the monolayer or -an increase in the proportion of cells with a higher cellular calcium content.…”

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confidence: 93%

Calcium and Age in Fibroblasts from Control Subjects and Patients with Cystic Fibrosis

Shapiro

Lam

1982

Science

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Intracellular calcium increases significantly as human fibroblasts age in culture. The calcium increase occurs 5 to 6 weeks (passages) earlier and is significantly greater in fibroblasts from subjects with cystic fibrosis in comparison with cells from control subjects. Intracellular calcium, which is thought to be a pathogenetic factor in cystic fibrosis, may also be a meaningful marker in cell aging.

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confidence: 93%