A new coumarin-derived fluorescent sensor with red-emission for Zn2+ in aqueous solution

Zinc(II) and pyrophosphate selective fluorescence probe and its application to living cell imaging

“…Disorders in Zn 2+ metabolism have been connected to several neurological diseases, including Alzheimer's disease (AD) [4,5], cerebral ischemia [6], and epilepsy [7]. Therefore, the development of techniques for Zn 2+ detection in biological processes has been an important research topic [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22].…”

Recent progress in development of 2,3-diaminomaleonitrile (DAMN) based chemosensors for sensing of ionic and reactive oxygen species

“…A coumarin-DAMN based uorescent sensor with longer emission wave length was developed in which 7-diethylamino group (electron donor) and DAMN (strong electron acceptor) were introduced into coumarin scaffold to generate an extensive donor-acceptor system which enhanced ICT process. 45 Although, synthesized sensor (14) exhibited weak uorescence due to the quenching effect of nitrile group as well as its exible structure, the intensity of emission peak at 620 nm was significantly increased up to 35-fold upon interaction with Zn 2+ ion along with blue shi of 50 nm. The enhancement of uorescence intensity was observed due to reduced ICT process and inhibition of conformational change upon combination with Zn 2+ ion.…”

Thiocarbazone‐appended coumarin: An easily accessible ratiometric fluorescent chemosensor for multianalyte (Zn2+ and Cu2+) systems

“…Coumarin derivatives have been used extensively as fluorescent chemosensors for the detection of metal ions because of their excellent fluorescence properties, such as high fluorescence quantum yield, long emission wavelengths and photostability. 11,12 Until now, a large number of fluorescent probes based on coumarin have been reported for the individual detection of Cu 2+11, [13][14][15][16][17][18][19][20][21][22] or Zn 2+12, [23][24][25][26][27][28][29][30][31][32][33][34][35] (Table 1). In general, the coordination of probes with Zn 2+ and Cu 2+ would enhance and quench the fluorescence due to the chelation-enhanced fluorescence (CHEF) effect of Zn 2+ ions 23,[26][27][28][29][30][31][32][33][34][35] and the paramagnetic of Cu 2+ ions, 17,19,21,22 respectively.…”