A New Concept of Capillary Circulation in Bone Cortex

Bone marrow circulation after osteotomy: Blood flow, pO2, pCO2, and pressure studied in dogs

“…The mechanism of nutritive supply which the endosteal bone will have to rely on after deprival of the main arterial supply is the periosteal supply. Normally a centrifugal blood supply nourishes the endosteal cortical bone (Brookes et al 1961, Rhinelander 1968, Kelly 1968. When this possibility is abolished, a change to a centripetal bone blood flow will have to come into action.…”

Scanning electron microscopy study of bone intracortical vessels using an injection and fractured surfaces technique

“…In a transmission electron microscopy study, Cooper et al (1966) documented nerve fibres around intracortical vessels; there is a good topographic correspondence between their ultrastructural findings and the surface filaments, therefore our interpretation is that they could correspond to The morphology of the intracortical vessels system 35 non-myelinated nerve fibres of the small intracortical vessels. The reported observations are based on morphology; however, they can have some relevance to our understanding of bone circulation physiology (Brookes et al 1961;Brookes and Revell 1998;Gross et al 1979;Cohen and Harris 1958). It is doubtful that these fibres could function to regulate blood flow by acting directly on the calibre of the small intracortical vessel, whose wall is formed only by the basal membrane and the endothelial cells.…”

Hemodynamics and metabolism in arthrosis: Studies in the rabbit knee

“…Joint incongruity and joint instability, which are both components of the arthrosis model, may affect the synovial membrane and cause joint effusion. This could lead to regional venous stasis, because of the intracapsular localisation of draining veins from the joint and the epiphysis (Brookes et al 1961). Joint effusion may therefore initiate haemodynamic and metabolic changes.…”