A new complex of copper-phosphole. Synthesis, characterization and evaluation of biological activity

Novel copper(I) complex of 2,5-Bis(2-pyridyl)phosphole: Synthesis, Characterization, Catalytic Activity and DFT Calculations

“…1 H and 13 C{ 1 H} NMR spectra showed very small differences compared to those of the free ligand suggesting a symmetric κ 1 (P)-coordination of the two phosphole ligands. Thus, NMR data at RT are consistent with a trigonal threecoordinate cooper(I) complex similar to [Cu{2,5-bis(2-thienyl)-1-phenyl-phosphole}2Cl] (2b) previously reported, [3] wherein the two phosphole ligands are κ 1 (P)-coordinated.…”

“…[42] Dihedral angle P1-C4-C5-N1 (20.2°) shows the torsion between the phosphole and pyridine rings of the bidentate ligand. Finally, Cu1-P2 (2.2449(8) Å) length corresponding to P-monodentate phosphole is shorter than the of P,N-chelate phosphole ligand, which is agree with κ 1 (P)phosphole ligands in copper(I) complexes [3]. Thus, XDR analysis reveals unambiguously that as-synthetized compound corresponds to a copper(I) complex with pseudo tetrahedral coordination geometry of the type [CuCl{k 1 (P)-1a}{k 2 (P,N)-1a}] instead a trigonal planar, as expected according to NMR data at RT.…”

“…They act as σ-donor ligand by using of the lone pair on phosphorus atom, π-donor ligand through of the dienic system, [1,2] and even, as polydentate ligand by introduction of pyridine, oxazoline, isoquinoline and amino-N type donor on the skeleton of phosphole. [3][4][5][6][7][8] Phosphole ligands with specific electronic and steric properties can be achieved by modification of the substituents at the C-atoms or at the P-atoms of the phosphole ring. For instance, the incorporation of aromatic substituents in 2,5-positions of ring creates an extended π-conjugated diene system which decrease the hyper-conjugation with the exocyclic P-R bond, reducing the aromaticity and increase σ-donor ability of phosphole.…”

Synthesis, characterization, and photophysical properties of a new 2,5-di(aryl)phosphole derivative and their trigonal copper–phosphole complexes

“…photophysical studies showed that all complexes exhibit fluorescence with quantum yields Φf = 0.04 -0.11, being the highest value for complex 2b. These new complexes open up the possibility of new researches in catalytic applications or studies of their biological activities as we have previously reported[16,44].…”

Synthesis, Characterization and Photophysical Properties of a New 2,5-Di(aryl)phosphole Derivative and Their Trigonal Copper-Phosphole Complexes

“…The photophysical studies showed that all complexes exhibit fluorescence with quantum yields Φf = 0.04 -0.11, being the highest value for complex 2b. These new complexes open up the possibility of new researches in catalytic applications or studies of their biological activitiesas we have previously reported[16,44].…”