A New Clinical Tool for Gait Evaluation in Parkinsonʼs Disease

Martinez‐Martín, Pablo; Urra, D. G.; Quijano, Teodoro del Ser; Gomez, Jocelyn; Utrero, E. Gomez; Piñeiro, Roi; Andres, Matthew

doi:10.1097/00002826-199706000-00001

Cited by 67 publications

(39 citation statements)

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“…Although previous studies have validated the use of the 3 m TUG test in PD,8 9 they examined subjects with more advanced disease compared with our group. Our PD subjects had an average H&Y 1.6, were 60 years old, and had an approximately 1 year's disease duration, whereas the other studies included subjects with H&Y 2.6 9 or ranging from 1 to 4,7 mean age between 67 7 and 69 years,9 and 9 years' disease duration 8. Our findings confirmed that a stopwatch measure is not sensitive to detect problems in people with PD, who do not show obvious clinical signs of impaired gait and balance.…”

Section: Discussionmentioning

confidence: 99%

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

Zampieri

Salarian

Carlson‐Kuhta

et al. 2009

Journal of Neurology, Neurosurgery & Psychiatry

309

259

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The Timed Up and Go (TUG) test has been used to assess balance and mobility in Parkinson’s Disease (PD). However, it is not known if this test is sensitive to subtle abnormalities present in early stages of the disease, when balance and gait problems are not clinically evident but may be detected with instrumented analysis of movement. We hypothesize that postural transitions and arm swing during gait will be the most sensitive characteristics of the TUG for early PD. In the present study, we instrumented the TUG test (iTUG) using portable inertial sensors, and extended the walking distance from 3 meters (traditional TUG) to 7 meters. Twelve subjects with early-to-moderate, untreated PD and 12 healthy individuals participated. Our findings show that although the stopwatch measure of TUG duration did not detect abnormalities in early-to-mid stage PD, the peak arm swing velocity on the more affected side, average turning velocity, cadence and peak trunk rotation velocity were significantly slower. These iTUG parameters were also correlated with the UPDRS Motor Scale. Thus, the iTUG test is sensitive to untreated PD and could potentially detect progression of PD and response to symptomatic and disease-modifying treatments.

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Section: Discussionmentioning

confidence: 99%

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

Zampieri

Salarian

Carlson‐Kuhta

et al. 2009

Journal of Neurology, Neurosurgery & Psychiatry

309

259

View full text Add to dashboard Cite

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“…51 However, the retropulsion test does not discriminate well between moderately affected patients and controls and is a poor predictor of falls in PD. 6 Many of the above tests are included in standardised rating scales, 52,53 but not all scales, e.g., the Tinetti Mobility Index, were specifically designed for use in PD and lack responsiveness in this population. 54 Whenever possible, patients should be examined both during optimal response to treatment and in a "defined off state" (after withdrawal of antiparkinson medication for at least 12 hours).…”

Section: Physical Examinationmentioning

confidence: 99%

Falls and freezing of gait in Parkinson's disease: A review of two interconnected, episodic phenomena

et al. 2004

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Falls and freezing of gait are two "episodic" phenomena that are common in Parkinson's disease. Both symptoms are often incapacitating for affected patients, as the associated physical and psychosocial consequences have a great impact on the patients' quality of life, and survival is diminished. Furthermore, the resultant loss of independence and the treatment costs of injuries add substantially to the health care expenditures associated with Parkinson's disease. In this clinically oriented review, we summarise recent insights into falls and freezing of gait and highlight their similarities, differences, and links. Topics covered include the clinical presentation, recent ideas about the underlying pathophysiology, and the possibilities for treatment. A review of the literature and the current state-of-the-art suggests that clinicians should not feel deterred by the complex nature of falls and freezing of gait; a careful clinical approach may lead to an individually tailored treatment, which can offer at least partial relief for many affected patients.

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“…There is, therefore, a need for reliable and valid outcome measures of walking ability. Evaluation of gait has traditionally been dominated by laboratory assessments, clinical assessments and gait tests that typically focus on capacity [3][4][5]. However, these do not necessarily capture walking difficulties in everyday life or the patients' perspectives.…”

Section: Introductionmentioning

confidence: 99%

Psychometric performance of a generic walking scale (Walk-12G) in multiple sclerosis and Parkinson’s disease

et al. 2011

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Walking difficulties are common in neurological and other disorders, as well as among the elderly. There is a need for reliable and valid instruments for measuring walking difficulties in everyday life since existing gait tests are clinician rated and focus on situation specific capacity. The Walk-12G was adapted from the 12-item multiple sclerosis walking scale as a generic patient-reported rating scale for walking difficulties in everyday life. The aim of this study is to examine the psychometric properties of the Walk-12G in people with multiple sclerosis (MS) and Parkinson's disease (PD). The Walk-12G was translated into Swedish and evaluated qualitatively among 25 people with and without various neurological and other conditions. Postal survey (MS, n = 199; PD, n = 189) and clinical (PD, n = 36) data were used to test its psychometric properties. Respondents considered the Walk-12G relevant and easy to use. Mean completion time was 3.5 min. Data completeness was good (<5% missing item responses) and tests of scaling assumptions supported summing item scores to a total score (corrected item-total correlations >0.6). Coefficient alpha and test-retest reliabilities were >0.9, and standard errors of measurement were 2.3-2.8. Construct validity was supported by correlations in accordance with a priori expectations. Results are similar to those with previous Walk-12G versions, indicating that scale adaptation was successful. Data suggest that the Walk-12G meets rating scale criteria for clinical trials, making it a valuable complement to available gait tests. Further studies involving other samples and application of modern psychometric methods are warranted to examine the scale in more detail.

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A New Clinical Tool for Gait Evaluation in Parkinsonʼs Disease

Cited by 67 publications

References 0 publications

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

Falls and freezing of gait in Parkinson's disease: A review of two interconnected, episodic phenomena

Psychometric performance of a generic walking scale (Walk-12G) in multiple sclerosis and Parkinson’s disease

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