A new carboxamide probe as On-Off fluorescent and colorimetric sensor for Fe3+ and application in detecting intracellular Fe3+ ion in living cells

Small-Molecule Fluorescent Probes for Binding- and Activity-Based Sensing of Redox-Active Biological Metals

“…To date, several other turn-off probes have been developed and subsequently employed in bio-imaging studies, by utilizing different fluorophores and heteroatom-substituted recognition groups. Included are dyes 42 – 46 that show fluorescence quenching due to ligand-to-metal charge-transfer (LMCT). − For instance, naphthol hydrazone-based NtHzBtd ( 45 ) contains a benzothiadiazole unit as the binding group . Sensor 45 exhibited a strong emission peak at 401 nm with a Stokes shift of 67 nm.…”

Bora‐Diaza‐Indacene Based Fluorescent Probes for Simultaneous Visualisation of Lipid Droplets and Endoplasmic Reticulum

“…Figure 1 shows the four dyes decorated with different functional groups synthesized for dual organelle imaging. The functional groups were chosen based on previous literature reports citing their use in developing organelle selective probes [28–30] . A criterion prioritized for the design of the below molecules was the lipophilicity index chosen to confer organelle selectivity.…”

Preparation and performance study of rhodamine B naphthylamide, a fluorescent probe, for the detection of Fe3+

“…Iron plays an important role in the vital functions of the human body, including hematopoietic function, oxygen storage and transport function, and immune function. 3 Iron deficiency can cause diseases such as iron deficiency anemia, 4 disorders of immune function, 5 heart failure, 6 and stroke, 7 whereas excessive iron intake can induce neurodegenerative diseases, 8 liver problems, 9 and tumors. 10 As a fundamental form of iron, Fe 3+ is widespread in the environment and living organisms and plays an important role in life activities.…”