A new birthweight reference in Guangzhou, southern China, and its comparison with the global reference

He, Jianxing; Xia, Huimin; Liu, Yu; Xia, Xiaoyan; Mo, Wenjian; Wang, Ping; Cheng, Kar Keung; Leung, Gabriel M.; Feng, Qiong; Schooling, CM; Qiu, Xiu

doi:10.1136/archdischild-2013-305923

Cited by 33 publications

(30 citation statements)

References 35 publications

(47 reference statements)

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“…Birthweight Z scores were calculated using a local population-based birth weight reference (He et al, 2014). LGA was defined as a birthweight larger than the 90th percentile for gestational age by gender, based on the same birth weight reference (He et al, 2014). Gestational age was estimated from ultrasound examination during the first- or second-trimester.…”

Section: Methodsmentioning

confidence: 99%

Single Fasting Plasma Glucose Versus 75-g Oral Glucose-Tolerance Test in Prediction of Adverse Perinatal Outcomes: A Cohort Study

Shen

Zhang

et al. 2017

EBioMedicine

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BackgroundThere remains uncertainty regarding whether a single fasting glucose measurement is sufficient to predict risk of adverse perinatal outcomes.MethodsWe included 12,594 pregnant women who underwent a 75-g oral glucose-tolerance test (OGTT) at 22–28 weeks' gestation in the Born in Guangzhou Cohort Study, China. Outcomes were large for gestational age (LGA) baby, cesarean section, and spontaneous preterm birth. We calculated the area under the receiver operator characteristic curves (AUCs) to assess the capacity of OGTT glucose values to predict adverse outcomes, and compared the AUCs of different components of OGTT.Results1325 women had a LGA baby (10.5%). Glucose measurements were linearly associated with LGA, with strongest associations for fasting glucose (odds ratio 1.37, 95% confidence interval 1.30–1.45). Weaker associations were observed for cesarean section and spontaneous preterm birth. Fasting glucose have a comparable discriminative power for prediction of LGA to the combination of fasting, 1 h, and 2 h glucose values during OGTT (AUCs, 0.611 vs. 0.614, P = 0.166). The LGA risk was consistently increased in women with abnormal fasting glucose (≥ 5.1 mmol/l), irrespective of 1 h or 2 h glucose levels.ConclusionsA single fasting glucose measurement performs comparably to 75-g OGTT in predicting risk of having a LGA baby.

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Section: Methodsmentioning

confidence: 99%

Single Fasting Plasma Glucose Versus 75-g Oral Glucose-Tolerance Test in Prediction of Adverse Perinatal Outcomes: A Cohort Study

Shen

Zhang

et al. 2017

EBioMedicine

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“…According to Baron and Kenny [21], mediation is demonstrated when the following conditions are met: (a) the main independent variable (SHS) is significantly associated with the main dependent variable (SGA, Models 1 and 2 in Table 3); (b) the independent variable (SHS) is significantly related to the mediator variable (placental weight in the multivariable linear model); and [3] the mediator variable (placental weight) is significantly associated with the dependent variable (SGA) when the independent variable (SHS) is controlled for (Model 3 in Table 3). The dichotomous outcomes in a mediation analysis [19] were treated by calculating the direct effect of SHS on SGA as the odds ratio (OR DE ) in Model 3 and the indirect effect (OR IE ) as the exponent of the product of the partial coefficient of SHS to SGA in Model 3 and of SHS to placental weight in the multivariable linear model.…”

Section: Discussionmentioning

confidence: 99%

“…We defined gestational age by combining the LMP estimate (gestational age ¼ delivery date À LMP) and the ultrasound estimate. Using a population of normal Cantonese newborns of 14e40 weeks of gestation [3] as a reference, we calculated the sex-and gestational-age-specific birth-weight Z-score as (individual birth weight À population mean)/(population standard deviation). Newborns with a birth-weight Z-score below À1.28 (equivalent to below the 10th percentile in a hypothetical normal distribution) were defined as SGA.…”

Section: Measurement Of Birth Weight and Definition Of Sgamentioning

confidence: 99%

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Placenta mediates the association between maternal second-hand smoke exposure during pregnancy and small for gestational age

et al. 2015

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“…Birth data between 2001 and 2015 were acquired from the Guangzhou Perinatal Health Care and Delivery Surveillance System (GPHCDSS), which has been described elsewhere 8, 22, 23 . In brief, the electronic GPHCDSS database was implemented in 2000, and covers over 99% of deliveries in Guangzhou (population: 13 million).…”

Section: Methodsmentioning

confidence: 99%

Birth weight changes in a major city under rapid socioeconomic transition in China

et al. 2017

Sci Rep

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Estimates of trends in birth weight may be useful in evaluating population health. We aimed to determine whether temporal changes in birth weight have occurred amongst 2.3 million neonates born in Guangzhou, China, during 2001–2015 and investigate the socioeconomic determinants of any changes. Trends in mean birth weight and annualized changes with the associated 95% confidence intervals (CIs) in the incidence of small for gestational age (SGA) and large for gestational age (LGA), defined as birth weight <10th or >90th centile respectively for gestational age and sex, were examined using linear and Poisson regression models. We found that mean birth weight declined by 1.07 grams/year from 2001 to 2015. After adjustment for gestational length, the decline in birth weight was attenuated (0.37 grams/year). The incidence of both SGA and LGA significantly decreased during the study period (annual decrease of 1.6% [95% CI, 1.5% to 1.7%] for SGA, 1.6% [95% CI, 1.5% to 1.8%] for LGA). We found a narrowing of disparities in SGA and LGA incidence across different maternal educational levels and residence location. Our results demonstrate that there has been an increase in the proportion of neonates born in the healthy birth weight range in Guangzhou.

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A new birthweight reference in Guangzhou, southern China, and its comparison with the global reference

Abstract: The new birthweight reference based on birthweight data for neonates in Guangzhou, China, differs from the reference currently used in China and the global reference, and appears to be more relevant to the local population.

Cited by 33 publications

References 35 publications

Single Fasting Plasma Glucose Versus 75-g Oral Glucose-Tolerance Test in Prediction of Adverse Perinatal Outcomes: A Cohort Study

Single Fasting Plasma Glucose Versus 75-g Oral Glucose-Tolerance Test in Prediction of Adverse Perinatal Outcomes: A Cohort Study

Placenta mediates the association between maternal second-hand smoke exposure during pregnancy and small for gestational age

Birth weight changes in a major city under rapid socioeconomic transition in China

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