A new biomarker panel for differential diagnosis of cholangiocarcinoma: Results from an exploratory analysis
Bruno Köhler,
Marta Bes,
Henry Lik-Yuen Chan
et al.
Abstract:Introduction Diagnosis of cholangiocarcinoma (CCA) can be challenging due to unclear imaging criteria and difficulty obtaining adequate tissue biopsy. Although serum cancer antigen 19-9 and carcinoembryonic antigen have been proposed as potential diagnostic aids, their use remains limited by insufficient sensitivity and specificity. This exploratory analysis aimed to identify individual- and combinations of serum biomarkers to distinguish CCA from hepatocellular carcinoma (HCC) and chronic liver disease (CLD) … Show more
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