A new bicornuate model of rat uterus transplantation
Dietrich Polenz,
Igor Maximilian Sauer,
Friederike Martin
et al.
Abstract:IntroductionUterus transplantation has revolutionized reproductive medicine for women with absolute uterine factor infertility, resulting in more than 40 reported successful live births worldwide to date. Small animal models are pivotal to refine this surgical and immunological challenging procedure aiming to enhance safety for both the mother and the child.Material and MethodsWe established a syngeneic bicornuate uterus transplantation model in young female Lewis rats. All surgical procedures were conducted b… Show more
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