A new approach to the analysis of skin blood flow oscillations in human

Grinevich, Andrey A.; Tankanag, Arina V.; Tikhonova, Irina V.; Chemeris, N. K.

doi:10.1016/j.mvr.2019.103889

Cited by 14 publications

(10 citation statements)

References 47 publications

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“…sample rate, length and prefiltering) may differ, and the methods can be sensitive to such variations in the parameters. Furthermore, recent work suggests that the frequency bands are not fixed and may vary, for example, with age or pathological state (Grinevich, Tankanag, Tikhonova, & Chemeris, ). Nevertheless, such frequency‐domain analysis is a valuable tool in understanding the processes modulating BF and their relative contribution to overall flow.…”

Section: Analysis In the Frequency Domainmentioning

confidence: 99%

Multiscale, multidomain analysis of microvascular flow dynamics

Chipperfield

Thanaj

Clough

2020

Experimental Physiology

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New Findings What is the topic of this review?We describe a range of techniques in the time, frequency and information domains and their application alone and together for the analysis of blood flux signals acquired using laser Doppler fluximetry. What advances does it highlight?This review highlights the idea of using quantitative measures in different domains and scales to gain a better mechanistic understanding of the complex behaviours in the microcirculation. Abstract To date, time‐ and frequency‐domain metrics of signals acquired through laser Doppler fluximetry have been unable to provide consistent and robust measures of the changes that occur in the microcirculation in healthy individuals at rest or in response to a provocation, or in patient cohorts. Recent studies have shown that in many disease states, such as metabolic and cardiovascular disease, there appears to be a reduction in the adaptive capabilities of the microvascular network and a consequent reduction in physiological information content. Here, we introduce non‐linear measures for assessing the information content of fluximetry signals and demonstrate how they can yield deeper understanding of network behaviour. In addition, we show how these methods may be adapted to accommodate the multiple time scales modulating blood flow and how they can be used in combination with time‐ and frequency‐domain metrics to discriminate more effectively between the different mechanistic influences on network properties.

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Section: Analysis In the Frequency Domainmentioning

confidence: 99%

Multiscale, multidomain analysis of microvascular flow dynamics

Chipperfield

Thanaj

Clough

2020

Experimental Physiology

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“…Analysis of literature showed that internal couplings were not earlier investigated, while external couplings were fragmentarily investigated in healthy volunteers, and they remain unstudied in type 2 DM patients. We have assessed for the first time the internal couplings characterizing the interaction between regulatory processes occurring in one part of microcirculatory bed in a small tissue volume [ 91 ]. Overlapping areas of adjacent frequencies with medium and strong internal couplings were found that characterized the interactions between regulatory mechanisms of skin blood flow: the central ones (respiratory and cardiac) and local (endothelial, neurogenic and myogenic).…”

Section: External and Internal Couplings Between The Regulatory Syste...mentioning

confidence: 99%

Skin Microhemodynamics and Mechanisms of Its Regulation in Type 2 Diabetes Mellitus

et al. 2022

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The review presents modern ideas about peripheral microhemodynamics, approaches to the ana-lysis of skin blood flow oscillations and their diagnostic significance. Disorders of skin microhemodynamics in type 2 diabetes mellitus (DM) and the possibility of their interpretation from the standpoint of external and internal interactions between systems of skin blood flow regulation, based on a comparison of couplings in normal and pathological conditions, including models of pathologies on animals, are considered. The factors and mechanisms of vasomotor regulation, among them receptors and signaling events in endothelial and smooth muscle cells considered as models of microvessels are discussed. Attention was drawn to the disturbance of Ca 2+ -dependent regulation of coupling between vascular cells and NO-dependent regulation of vasodilation in diabetes mellitus. The main mechanisms of insulin resistance in type 2 DM are considered to be a defect in the number of insulin receptors and impaired signal transduction from the receptor to phosphatidylinositol-3-kinase and downstream targets. Reactive oxygen species plays an important role in vascular dysfunction in hyperglycemia. It is assumed that the considered molecular and cellular mechanisms of microhemodynamics regulation are involved in the formation of skin blood flow oscillations. Parameters of skin blood microcirculation can be used as diagnostic and prognostic markers for assessing the state of the body.

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“…Using Matlab 2016 (MathWorks Inc., Natick, MA, USA), the signal noise was filtered and the SBF perfusion was calculated. Similar to previous studies [34][35][36][37][38], a Morlet wavelet transform was used to determine BFO. Five characteristic frequencies in the frequency interval between 0.0095 and 2 Hz were identified.…”

Section: Blood Flow Perfusion and Oscillation Analysismentioning

confidence: 99%

“…Furthermore, blood flow oscillation (BFO) reflects the current functional state of blood flow regulation systems. BFO analysis shows that characteristic frequencies reflect endothelial activity (0.008-0.02 Hz), sympathetic neurogenic activity (0.02-0.06 Hz), myogenic activity (0.06-0.2 Hz), respiratory activity (0.2-0.6 Hz), and cardiac activity (0.6-2.3 Hz) [34][35][36][37][38][39].…”

Section: Introductionmentioning

confidence: 99%

The Recovery Benefit on Skin Blood Flow Using Vibrating Foam Rollers for Postexercise Muscle Fatigue in Runners

Lai

Wang

Yang

et al. 2020

IJERPH

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Purpose: To determine the effect of vibrating rollers on skin blood flow after running for recovery from muscle fatigue. Method: 23 healthy runners, aged between 20 to 45 years, participated in a crossover trial. Muscle fatigue was induced by running, and recovery using a vibrating roller was determined before and after the intervention. Each subject was measured at three time points (prerun, postrun, and postroller) to compare skin blood flow perfusion and blood flow oscillation at the midpoint of the dominant gastrocnemius muscle. The results show that blood perfusion is greater when a vibrating roller is used than a foam roller, but there is no statistical difference. The analysis of blood flow oscillation shows that vibrating rollers induce 30% greater endothelial activation than a foam roller. Vibrating rollers significantly stimulate the characteristic frequency for myogenic activation (p < 0.05); however, the effect size is conservative.

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A new approach to the analysis of skin blood flow oscillations in human

Cited by 14 publications

References 47 publications

Multiscale, multidomain analysis of microvascular flow dynamics

Multiscale, multidomain analysis of microvascular flow dynamics

Skin Microhemodynamics and Mechanisms of Its Regulation in Type 2 Diabetes Mellitus

The Recovery Benefit on Skin Blood Flow Using Vibrating Foam Rollers for Postexercise Muscle Fatigue in Runners

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