A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones

Recent advances in 4(3H)-quinazolinone syntheses

“…A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones and its derivatives using the condensation reaction of substituted 2-aminobenzamide and ortho esters is reported by Huang in 2011. 36 Interestingly, the reaction proceeds without organic solvent and in the absence of basic or acidic catalyst.…”