A new approach for paper-based analytical devices with electrochemical detection based on graphite pencil electrodes

Santhiago, Murilo; Kubota, Lauro T.

doi:10.1016/j.snb.2012.11.002

Cited by 126 publications

(95 citation statements)

References 41 publications

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“…Briefly, this sensor is made by drawing interdigitated electrodes over paper with a graphite pencil in the "pencil-on-paper" approach already used by many research groups [23][24][25][26]. Over the interdigitated pencil electrodes(inside a paper surface of 1cm2),one drop (30µL) of an aqueous suspension of ZnO crystals (Sigma Aldrich <100nm) is deposited and dried over a hot plate for 5 minutes at 120 o C. The sensor microscopic structure and chemical composition mapping of the sensor surface is studied using aJeolJXA-8530F HyperProbe Electron Probe Micro Analyzer (EPMA).…”

Section: Methodsmentioning

confidence: 99%

Paper-Based ZnO Oxygen Sensor

et al. 2015

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In this work we report the development of an oxygen sensor using a simple device made from a film of ZnO crystals dispersed over a paper surface. Due to the high porosity of this kind of device made from paper and ZnO, a large photoconductive effect is observed as result of the fast absorption and desorption of oxygen from the ZnO surface. To detect oxygen we propose to use ultraviolet (UV) illumination over the photoconductive surface of the sensor, the applied UV light produces oxygen desorption causing current variations through the sensor that are proportional to the oxygen presence nearby the sensor surface. The sensor developed in this work is attractive because it is remarkably easy to fabricate, employs only very low cost materials for its construction and shows a better sensitivity at low concentration of oxygen at partial vacuum environments.

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Section: Methodsmentioning

confidence: 99%

Paper-Based ZnO Oxygen Sensor

et al. 2015

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“…The use of carbon as a base material to construct screen-printing devices have been employed, during the last decades, because it has adequate properties that allows not only its simple use as porous materials, but also it permits surface modification and is cheap [5][6][7][8][9]. Fabrication of paper-based devices has also been developed in the last ten years, but still it is a challenge.…”

Section: Introductionmentioning

confidence: 99%

“…Paper is an environmental friend material, easily manipulated, cheap, and biocompatible; has high adaptability for analysis of different substances. These properties make paper the perfect physic base for introducing microfluidic channels and to be used in Point-of-care devices [5,[8][9][10]. One disadvantage of The use of disposable and miniaturized biosensors that can detect subtract, like glucose and ethanol, in biological fluid or in food, with accuracy has been developed since the nineties [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Achieving Enzyme Stability Using a Simple Fabrication Procedure: The Alcohol Dehydrogenase Example

Ribau¹,

Fortunato²

2018

JPP

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Abstract:The use of screen-printing biosensors has been updated in this article as a tool to analyze the electron transfer process involving redox proteins or enzymes. The aim of this research was to fabricate a simple apparatus which allowed the use of the enzymes (in the solid state) to maintain their stability. To prove this concept an enzyme in the solid state was mixed with the carbon ink and this mixture was used to print the working electrode. We choose as proving the alcohol dehydrogenase. The first reason is because it metabolizes the alcohol, which can be present in biological samples of blood, saliva and urine and also in the beverage; the second is that this enzyme is still a challenge to electrochemistry due to having lower stability in sensors. The results show that in this device the enzyme was active and stable during all the experiments and in the experimental conditions that could catalyze the ethanol to acetaldehyde. These devices have the advantage of being disposable, cheap and are easy to fabricate. And also, they do not need expensive tools to be fabricated, they only need 2 µL of electrolyte or sample, and they need lower amounts of enzyme to permit electrochemical studies.

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“…Podem ainda ser confeccionados os eletrodos usando métodos mais sofisticados como a deposição metálica por sputtering [42,43]. Para uso de eletrodos carbonáceos, além do uso de tinta condutiva, há trabalhos que fazem o uso do grafite [44,45] e da pintura direta no papel com minas de grafite [46][47][48]. Uma abordagem alternativa é o uso de fios metálicos fixados sobre a superfície do substrato de papel [49,50].…”

Section:  Análises Químicas Tradicionais De Drogas De Abusounclassified

“…No campo que concerne o desenvolvimento de sensores eletroquímicos descartáveis e portáteis, há diversas pesquisas realizadas na literatura para a fabricação de eletrodos do tipo impressos através de diferentes tecnologias, mas basicamente utilizando tintas condutivas de carbono e outros metais [125][126][127], utilizando fios metálicos [49,128], construção de dispositivos em circuitos eletrônicos [78,129], confecção a partir de CDs (CDtrodos) [130][131][132], utilização direta de grafites [45,101] ou ainda "pintando/desenhando" com grafite sobre um substrato, comumente papel [47,48], entre outras formas.…”

Section: Preâmbulounclassified

Desenvolvimento de sensores eletroquímicos e colorimétricos para aplicações em amostras de interesse forense

Araújo¹

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A new approach for paper-based analytical devices with electrochemical detection based on graphite pencil electrodes

Cited by 126 publications

References 41 publications

Paper-Based ZnO Oxygen Sensor

Paper-Based ZnO Oxygen Sensor

Achieving Enzyme Stability Using a Simple Fabrication Procedure: The Alcohol Dehydrogenase Example

Desenvolvimento de sensores eletroquímicos e colorimétricos para aplicações em amostras de interesse forense

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