A New Anti-Ag Serum (Serum B.N.)

Polymorphisms of the Human Low-Density Lipoproteins

“…In a later publication the same author reports the discovery of 19 sera with isoprecipitins from 110 tested patients, all of which had received over 40 transfusions [16]. Hirschfeld and Blombäck [34], in the course of a study of the sera of 24 patients which had re ceived many transfusions because of a hereditary coagulopathy found only one serum with isoprecipitins, and this in a patient who had received over 300 blood or plasma transfusions. Among 214 patients, all of whom had received more than 20 transfusions we have found two sera with isoprecipitins [27].…”

“…The panel, further more, should contain sera of different population groups because more information about the specificity of the factors could be gained * We are indebted to Dr. J. Hirschfeld, Stockholm, for performing this in vestigation. Hirschfeld and Blombäck, 1964 [34] Ag(x) Ag(ai) based on the expected differences in their distribution. Blumberg [17] has already earlier called the attention to these points.…”

Comparative Studies on Anti-Ag Sera in Immunodiffusion and in Passive Hemagglutination Methods

“…: doubtful reaction. Remark: The LDL used (6,7,8,9,10,12,15, 33 and 36) gave positive reactions in the immunodiffusion test with the serum RO. with the sera PZ II and GH II using Ag(x+)-LDL preparations (LDL 7 and LDL 15) with the total of the 48 panel sera gave positive inhibition with all Ag(x+) sera except for one serum (serum 11 did not inhibit PZ II).…”

Conceptual Framework Shifts in Immunogenetics

“…At this six-reagent level of analysis of two Caucasian population materials, the Ag sys tem can thus, in a simple-complex theory, be regarded as a three locus system. Each locus (Agxly, AgaJd, Agdg) has two 'antithetical' or contrasting alleles with codominant inheritance as discussed elsewhere [2,3,[5][6][7][8][9], cross-reacting reagent(s), e.g. anti-AC; anti-ABCwhich in their RR values 'include' the RR value of the 'short' or more 'specific' reagent.…”