A new analytical method for the simultaneous quantification of isoflavones and lignans in 25 green coffee samples by HPLC-MS/MS

Angeloni, Simone; Navarini, Luciano; Khamitova, Gulzhan; Maggi, Filippo; Sagratini, Gianni; Vittori, Sauro; Caprioli, Giovanni

doi:10.1016/j.foodchem.2020.126924

Cited by 30 publications

(19 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Then, supernatants were transferred to a fresh microcentrifuge tube and dried in a vacuum evaporator. After drying, the metabolites were redissolved with 80% methanol and analyzed by the HPLC-MS/MS platform [39]. Next, the data were extracted using Compound Discover V3.1 (CD) software, including noise filtering, retention time alignment, mass spectrometry peak extraction, compound mapping between samples, compound identification, gap filling, and background subtracting.…”

Section: Untargeted Metabolomics Analysismentioning

confidence: 99%

Transcriptome and Metabolome Analysis Revealed the Freezing Resistance Mechanism in 60-Year-Old Overwintering Camellia sinensis

Wang

et al. 2021

Biology

View full text Add to dashboard Cite

Freezing stress in winter is the biggest obstacle to the survival of C. sinensis in mid-latitude and high-latitude areas, which has a great impact on the yield, quality, and even life of C. sinensis every year. In this study, transcriptome and metabolome were used to clarify the freezing resistance mechanism of 60-year-old natural overwintering C. sinensis under freezing stress. Next, 3880 DEGs and 353 DAMs were obtained. The enrichment analysis showed that pathways of MAPK and ABA played a key role in the signal transduction of freezing stress, and Pyr/PYL-PP2C-SnRK2 in the ABA pathway promoted stomatal closure. Then, the water holding capacity and the freezing resistance of C. sinensis were improved. The pathway analysis showed that DEGs and DAMs were significantly enriched and up-regulated in the three-related pathways of phenylpropanoid biosynthesis, flavone and flavonol biosynthesis, and flavonoid biosynthesis. In addition, the carbohydrate and fatty acid synthesis pathways also had a significant enrichment, and the synthesis of these substances facilitated the freezing resistance. These results are of great significance to elucidate the freezing resistance mechanism and the freezing resistance breeding of C. sinensis.

show abstract

Section: Untargeted Metabolomics Analysismentioning

confidence: 99%

Transcriptome and Metabolome Analysis Revealed the Freezing Resistance Mechanism in 60-Year-Old Overwintering Camellia sinensis

Wang

et al. 2021

Biology

View full text Add to dashboard Cite

show abstract

“…The data revealed active components in the pure extract of CWE with low concentrations of carbohydrates, alkaloids, proteins, amino acids, saponins, and flavonoids. Furthermore, tannins and phenols can be used in high concentrations in chlorogenic acid, gallic acid, and caffeic acid [17,19,26]. This proves the waste's effectiveness and potential to preserve the active ingredients in the used coffee powder.…”

Section: Phytochemical Screeningmentioning

confidence: 86%

“…HPLC method was used to detect main compounds in CWE, and the experimental was typically conducted as published elsewhere [26,27]. UV-vis spectrophotometer (ATI Unicam 5625 UV/VIS Vision Software V3.20) was used to screen the as-synthesized AgNPs in the range of 200-800 nm.…”

Section: The Main Characterization Of Cwe and Cwe Capped Agnpsmentioning

confidence: 99%

Synthesis of silver nanoparticles using bio valorization coffee waste extract: photocatalytic flow-rate performance, antibacterial activity, and electrochemical investigation

El-Desouky

Shoueir

El‐Mehasseb

et al. 2022

Biomass Conv. Bioref.

View full text Add to dashboard Cite

It is well known that biogenic synthesis, as compared to other processes, has proven to be highly effective in the fabrication of silver nanoparticles (AgNPs). Thus, our current study focused on synthesizing AgNPs using coffee waste extract (CWE). CWE contains many compounds identified by HPLC, which reduce, cap, and stabilize AgNPs in its solution. The as-synthesized AgNPs were produced with a monodispersed small size around 20 nm and exhibited in-plane dipole plasmon resonances of hexagonal nanoplates. AgNPs were characterized by both physical and spectroscopic methods, which confirmed their nanoscale dimensions with a hexagonal shape. The as-prepared AgNPs (12 mg) enabled the photodegradation of phenol compounds (20 mL) with a removal efficiency of ~ 94.6% in a short time in the presence of citric acid. Additionally, the second promising application of AgNPs was the tendency to remove the hazard 2,4 dinitroaniline (2,4 DNA) with a percent more than 97% while using only 7 mg of AgNPs. Moreover, the green synthesized AgNPs are superior in inhibiting bacterial growth and killing most infected microbes such as B. subtilis , P. aeruginosa , S. aureus , and E. coli . The electrochemical characteristics of the AgNPs were evaluated using a three-electrode system. The calculated specific capacitance was 280 F g −1 at 0.56 A g −1 . Furthermore, after 1000 cycles at 2.2 A g −1 , the AgNPs electrode demonstrates an excellent cycling stability behavior with 94.8% capacitance retention. Based on the previous promising results, it can be concluded that CWE is an environmentally benign extract to prepare AgNPs with low cost, saving and easily used for many great domains in photocatalytic, phenol compound removals, and production of functional nanodevices.

show abstract

“…Besides containing daidzin, genistin, daidzein, genistein, formononetin, and biochanin A, green coffee also contains three lignans, secoisolariciresinol, matairesinol, and lariciresinol. Flavonolignan (silychristine, silybinine, and isosilybinin) is found in the milk thistle fruit [10].…”

Section: Figurementioning

confidence: 99%

The Beneficial and Adverse Effects of Phytoestrogens

Blázovics¹,

Csorba²,

Ferencz³

2022

OBM ICM

View full text Add to dashboard Cite

The most well-known phytoestrogens (flavonoids, isoflavonoids, lignans, coumestans, stilbenes, and prenylflavonoids) are isoflavonoids, which are important active ingredients in medicinal and food plants. They are highly abundant in the Fabaceae family. More than 1,000 types of isoflavonoids have been isolated from nearly 300 kinds of plants, and more are being discovered through modern analytical methods. Glycosides O and C of isoflavonoids are poorly absorbed in the intestine. They are converted by bacterial esterases and/or β-glycosidase enzymes to aglycones, which are absorbed more efficiently. Their bioavailability shows significant differences due to variation in the intestinal microflora of various races. The compounds formed during their biotransformation are structurally similar to estrogens. In Traditional Chinese medicine, several herbs rich in phytoestrogens are used to prevent and cure various diseases, such as osteoporosis, cardiovascular diseases, diabetes mellitus, hypertension, hyperlipidemia, tumors, and inflammation; additionally, 185 herbs are used to treat menopausal symptoms. Some of these herbs can be used to alleviate the unpleasant symptoms of menopause and treat breast and prostate cancer. From a nutritional physiology perspective, the consumption of Glycine max and Vigna unguiculata should be emphasized. Soy has been consumed in China for about 5,000 years while it was introduced to Europe nearly 300 years ago. Soybean cultivation in Hungary dates back only 100 years. The assessment of the efficacy of phytoestrogens is unclear. Although several experimental and molecular biology studies have shown favorable results, studies on humans have not shown prominent therapeutic benefits. However, comparing and interpreting the findings of modern studies might elucidate the therapeutic utility of phytoestrogens.

show abstract

A new analytical method for the simultaneous quantification of isoflavones and lignans in 25 green coffee samples by HPLC-MS/MS

Cited by 30 publications

References 21 publications

Transcriptome and Metabolome Analysis Revealed the Freezing Resistance Mechanism in 60-Year-Old Overwintering Camellia sinensis

Transcriptome and Metabolome Analysis Revealed the Freezing Resistance Mechanism in 60-Year-Old Overwintering Camellia sinensis

Synthesis of silver nanoparticles using bio valorization coffee waste extract: photocatalytic flow-rate performance, antibacterial activity, and electrochemical investigation

The Beneficial and Adverse Effects of Phytoestrogens

Contact Info

Product

Resources

About