A new 90Sr/90Y radioisotope generator

Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease

“…However, since 90 Y and 90 Sr have such distinctly different half-lives, they represent a daughter/parent radionuclide combination that is ideal for incorporation into a generator system. Numerous generator systems have been developed where the 90 Sr is adsorbed onto a solid support and the 90 Y is eluted using lactate,285 methanol and acetate,286 oxalate,287 citrate288 or EDTA 289,290. Recently, Chakravarty et al developed the Kamadhenu generator 291.…”

Complexation studies with 90Y from a novel 90Sr-90Y generator

“…A number of solvent extraction and ion exchange methods have been reported for the separation of 90 Y from 90 Sr [15][16][17][18]. In most of those generators, 90 Y is eluted as a complex which is then destroyed to obtain 90 Y(III) for preparation of the complex of interest.…”

Simple and safe production of yttrium-90 from a new type of 90Sr/90Y generator

“…The spectrum of pure 90 Y was obtained by extracting the 90 Y into 2-thenoyltrifluoroacetone according to Goldin [12]. The 90 Sr breakthrough then can be calculated by measuring the sample count rate in the energy range 50-300 keV and > 600 keV as previously described method [7].…”

“…Since the use of generator-produced 90 Y would considerably reduce the cost of this radionuclide and also provide the required activity when necessary, several generator system based on ion exchange methods have been reported in the literature. In most of them, cationic exchange resins were used to absorb the ionic 90 Sr while the 90 Y activity is eluted with lactate [3], oxalate [4], citrate [5], α-hydroxyisobutyrate [6] and EDTA [7,8]. A disadvantage *Author for correspondence (E-mail: dujin@bjmu.edu.cn).…”