“…This groundwork of neuroanatomical knowledge helped identify a role for PB neurons in a wide variety of homeostatic functions. These include taste signaling (Norgren, 1976; Norgren & Leonard, 1971, 1973), hunger (Carter, Han, & Palmiter, 2015; Carter, Soden, Zweifel, & Palmiter, 2013; Garfield et al, 2015; Kim et al, 2020; Li et al, 2019; Wu, Clark, & Palmiter, 2012), thirst and sodium appetite (Geerling et al, 2011; Lee et al, 2019; Park, Williams, Liu, & Sohn, 2020; Ryan, Ross, Campos, Derkach, & Palmiter, 2017), thermoregulation (Geerling et al, 2016; Nakamura & Morrison, 2008, 2010; Yahiro, Kataoka, Nakamura, & Nakamura, 2017), nociception (Bester, Menendez, Besson, & Bernard, 1995; Chiang et al, 2019), breathing (Chamberlin & Saper, 1994; St John, Glasser, & King, 1972), hypercapnic arousal (Kaur et al, 2013; Kaur et al, 2017), cardiovascular control (Chamberlin & Saper, 1992; Miller et al, 2012), itch (Mu et al, 2017), and alarm (Campos, Bowen, Roman, & Palmiter, 2018; Palmiter, 2018; Saper, 2016).…”