Abstract:Background: Osteoporosis (OP) is determined as a chronic systemic bone disorder to increase the susceptibility to fracture. Ginsenosides have been found the anti-osteoporotic activity of in vivo and in vitro. However, its mechanism remains unknown.Methods: The potential mechanism of ginsenosides in anti-osteoporotic activity was identified by using network phamacology analysis. The active compounds of ginsenosides and their targets associated to OP were retrieved from Traditional Chinese Medicine Systems Pharm… Show more
“…29 Ginsenosides are a class of sterol compounds with tetracyclic structures and carbohydrate steroids. 30 They can be divided into dammarane and oleanane according to different aglycone frameworks (Fig. 1).…”
“…29 Ginsenosides are a class of sterol compounds with tetracyclic structures and carbohydrate steroids. 30 They can be divided into dammarane and oleanane according to different aglycone frameworks (Fig. 1).…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.