A nationwide study of air pollution from particulate matter and daily hospitalizations for respiratory diseases in Italy

Renzi, Matteo; Scortichini, Matteo; Forastiére, Francesco; Donato, Francesca De'; Michelozzi, Paola; Davoli, Marina; Gariazzo, Claudio; Viegi, Giovanni; Stafoggia, Massimo; Ancona, Carla; Bucci, Simone; Bonafede, Michela; Marinaccio, Alessandro; Stefania, Argentini; Sozzi, Roberto; Bonomo, Sergio; Fasola, Salvatore; Grutta, Stefania La; Cernigliaro, Achille; Scondotto, Salvatore; Baldacci, Sandra; Maio, Sara; Licitra, Gaetano; Moro, Ali; Angelini, Paola; Bonvicini, Laura; Broccoli, Serena; Ottone, Marta; Rossi, Paolo; Colacci, Annamaria; Parmagnani, Federica; Ranzi, Andrea; Galassi, Claudia; Migliore, Enrica; Bisceglia, Lucia; Antônio, Carlos Roberto; Basso, Giuseppe; Calori, Giuseppe; Finardi, S.; Pepe, Nicola; Radice, Paola; Silibello, Camillo; Tinarelli, G.; Uboldi, Francesco; Carlino, Giuseppe

doi:10.1016/j.scitotenv.2021.151034

Cited by 26 publications

(8 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, we observed more acute and larger effects of air pollutants on CVD‐DM and RD‐DM among elder patients than CVD and DR without combined DM reported by other epidemiological studies (Rahman et al., 2021; Renzi et al., 2022). A study from Italy reported an effect of PM 2.5 and PM 10 on CVD patients at lag05, while Yu et al.…”

Section: Discussionsupporting

confidence: 68%

Causal Associations of Air Pollution With Cardiovascular Disease and Respiratory Diseases Among Elder Diabetic Patients

Liu

et al. 2023

GeoHealth

View full text Add to dashboard Cite

Extensive researches have linked air pollutants with cardiovascular disease (CVD) and respiratory diseases (RD), however, there is limited evidence on causal effects of air pollutants on morbidity of CVD or RD with comorbidities, particularly diabetes mellitus in elder patients. We included hospital admissions for CVD or RD among elder (≥65 years) diabetic patients between 2014 and 2019 in Beijing. A time‐stratified case‐crossover design based on negative‐control exposure was used to assess causal associations of short‐term exposure to air pollutants with CVD and RD among diabetic patients with the maximum lag of 7 days. A random forest regression model was used to calculate the contribution magnitude of air pollutants. A total of 493,046 hospital admissions were recorded. Per 10 μg/m3 uptick in PM1, PM2.5, PM10, SO2, NO2, O3, and 1 mg/m3 in CO was associated with 0.29 (0.05, 0.53), 0.14 (0.02, 0.26), 0.06 (0.00, 0.12), 0.36 (0.01, 0.70), 0.21 (0.02, 0.40), −0.08 (−0.25, 0.09), and 4.59 (0.56, 8.61) causal effect estimator for admission of CVD among diabetic patients, corresponding to 0.12 (0.05, 0.18), 0.09 (0.05, 0.13), 0.05, 0.23 (0.06, 0.41), 0.10 (0.02, 0.19), −0.04 (−0.06, −0.01), and 3.91(1.81, 6.01) causal effect estimator for RD among diabetic patients. The effect of gaseous pollutants was higher than particulate pollutants in random forest model. Short‐term exposure to air pollution was causally associated with increased admission of CVD and RD among elder diabetic patients. Gaseous pollutants had a greater contribution to CVD and RD among elder diabetic patients.

show abstract

Section: Discussionsupporting

confidence: 68%

Causal Associations of Air Pollution With Cardiovascular Disease and Respiratory Diseases Among Elder Diabetic Patients

Liu

et al. 2023

GeoHealth

View full text Add to dashboard Cite

show abstract

“…This study found no statistically significant association between the other four air pollutants and COPD admissions. However, studies had shown that PM 2.5 and PM 10 were important risk factors for COPD (Lin et al 2020 ; Peng et al 2022 ; Pini et al 2021 ; Renzi et al 2022 ). A study in China found that PM 2.5 was strongly associated with increased admission for COPD (Zhang et al 2020 ).…”

Section: Discussionmentioning

confidence: 99%

Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements

Cheng

Han

Fang

et al. 2023

Environ Sci Pollut Res

View full text Add to dashboard Cite

Evidence between air pollution and chronic obstructive pulmonary disease (COPD) is inconsistent and limited in China. In this study, we aim to examine the associations between air pollutants and hospital admissions for COPD, hoping to provide practical advice for prevention and control of COPD. Hospital admissions for COPD were collected from a Grade-A tertiary hospital in Jinan from 2014 to 2020. A generalized additive model (GAM) was used to examine the associations between air pollutants and hospital admissions for COPD. Stratified analysis was also conducted for gender, age (20–74 and ≥75 years), and season (warm and cold). The avoidable number of COPD hospital admissions was calculated when air pollutants were controlled under national and WHO standards. Over the study period, a total of 4,012 hospital admissions for COPD were recorded. The daily hospital admissions of COPD increased by 2.36% (95% CI : 0.13–4.65%) and 2.39% (95% CI : 0.19–4.65%) for per 10 μg/m 3 increase of NO 2 and SO 2 concentrations at lag2, respectively. There was no statistically significant difference in health effects caused by increased concentrations of PM 2.5 , PM 10 , CO, and O 3 . The health effects of increased SO 2 concentration were stronger in women, the ≥75 years old people and the cold season. About 2 (95% CI : 0–3), 64 (95% CI : 4–132) and 86 (95% CI : 6–177) COPD admissions would be avoided when the SO 2 concentration was controlled below the NAAQS-II (150 μg/m 3 ), NAAQS-I (50 μg/m 3 ), and WHO’s AQG2021 standard (40 μg/m 3 ), respectively. These findings suggest that short-term exposure to NO 2 and SO 2 was associated with increased risks of daily COPD admissions, especially for females and the elderly. The control of SO 2 and NO 2 under the national and WHO standards could avoid more COPD admissions and obtain greater health benefits. Supplementary Information The online version contains supplementary material available at 10.1007/s11356-023-25567-8.

show abstract

“…According to the European Environment Agency, particulate matter (PM 2,5 ) is one of the main causes of premature death and health problems in Europe (EEA 2021b ). Several studies carried out in Italy over the last few years have analyzed the relationship between air pollution levels and hospital admissions due to different diseases (Gandini et al 2018 ; Renzi et al 2022 ). These studies have shown how long- and short-term exposure to air pollutants, even in low levels, has an impact on the number of hospital admissions for respiratory diseases, with an increased risk in older people, those with low economic incomes, smokers, or those with unhealthy working conditions.…”

Section: Introductionmentioning

confidence: 99%

Environmental pollution in North-Eastern Italy and its influence on chronic obstructive pulmonary disease: time series modelling and analysis using visibility graphs

Aranburu-Imatz

Jiménez-Hornero

Morales‐Cané

et al. 2023

Air Qual Atmos Health

View full text Add to dashboard Cite

The impact on human health from environmental pollution is receiving increasing attention. In the case of respiratory diseases such as chronic obstructive pulmonary disease (COPD), the relationship is now well documented. However, few studies have been carried out in areas with low population density and low industrial production, such as the province of Belluno (North-Eastern Italy). The aim of the study was to analyze the effect of exposure to certain pollutants on the temporal dynamics of hospital admissions for COPD in the province of Belluno. Daily air pollution concentration, humidity, precipitations, and temperature were collected from the air monitoring stations in Belluno. Generalized additive mixed models (GAMM) and visibility graphs were used to determine the effects of the short-term exposure to environmental agents on hospital admissions associated to COPD. In the case of the city of Belluno, the GAMM showed that hospital admissions were associated with NO2, PM10, date, and temperature, while for the city of Feltre, GAMM produced no associated variables. Several visibility graph indices (average edge overlap and interlayer mutual information) showed a significant overlap between environmental agents and hospital admission for both cities. Our study has shown that visibility graphs can be useful in establishing associations between environmental agents and COPD hospitalization in sparsely populated areas.

show abstract

A nationwide study of air pollution from particulate matter and daily hospitalizations for respiratory diseases in Italy

Cited by 26 publications

References 37 publications

Causal Associations of Air Pollution With Cardiovascular Disease and Respiratory Diseases Among Elder Diabetic Patients

Causal Associations of Air Pollution With Cardiovascular Disease and Respiratory Diseases Among Elder Diabetic Patients

Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements

Environmental pollution in North-Eastern Italy and its influence on chronic obstructive pulmonary disease: time series modelling and analysis using visibility graphs

Contact Info

Product

Resources

About