A national series of 244 sinonasal cancers in Finland in 1990–2004

Koivunen, Petri; Mäkitie, Antti; Bäck, Leif; Pukkila, Matti; Laranne, Jussi; Kinnunen, Ilpo; Aitasalo, Kalle; Grénman, Reidar

doi:10.1007/s00405-011-1615-x

Cited by 34 publications

(37 citation statements)

References 17 publications

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“…As we found in our study, the predominance of men was obvious in previous works (10,11). The majority of neoplasms occurred in the fifth decade of life which are in support with findings in previous studies (2,3).…”

Section: Discussionsupporting

confidence: 85%

Paranasal sinuses malignancies: A 12-year review of clinical characteristics

Danesh-Sani

Sarafraz²,

Chamani³

et al. 2016

Med Oral

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BackgroundInadequate epidemiologic investigations of the paranasal sinuses malignancies prompted this retrospective study with special emphasis on a major group of 111 tumors.Material and MethodsClinical records of 111 patients with histologically confirmed malignant tumors of the paranasal sinuses were investigated retrospectively from April 2000 to January 2012. Collection of data included demographic information, clinical manifestations, treatment plans, and histopathology of the tumor.ResultsThere were 69 (62.16%) male and 42 (37.83%) female patients (male-to-female ratio of 1.6:1), with a median age of 49±12.2 years (range 21 to 88 years). A high level of occurrence was noticed in the fifth (26.3%) decade of life. The most frequent histological types were squamous cell carcinoma (43.5%) and adenoid cystic carcinoma (19%). Among clinical manifestations, nasal obstruction was the most frequent followed by diplopia, and facial swelling. Fifty three patients (47.74%) were treated with combined approach of surgery and radiation therapy.ConclusionsParanasal sinuses malignancies are rare conditions with nonspecific symptoms which make early diagnosis of the lesions more challenging. The optimal therapeutic protocol for patients suffering from these tumors is still a somewhat controversial entity and requires further studies. Key words:Paranasal sinuses, malignancy, surgery,radiotherapy.

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Section: Discussionsupporting

confidence: 85%

Paranasal sinuses malignancies: A 12-year review of clinical characteristics

Danesh-Sani

Sarafraz²,

Chamani³

et al. 2016

Med Oral

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“…consider that "rhinomaxillary syndrome" is pathognomonic of lepromatous leprosy only when the full spectrum of lesions is present, but this is not the case of either skeleton 3 or 6. Even if this were the case the pathognomonic value of this syndrome is not consensual because this anatomical region may be involved in many other disease processes such as mucocutaneous leishmaniasis (Herwaldt, 1999;Manchester, 1994;Aufderheide and Rodríguez-Martín, 1998;Ortner, 2003;Malekpour and Esfandbod, 2010;Marsteller et al, 2011), neoplasms (Hackett, 1976;Aufderheide and Rodríguez-Martín, 1998;Ortner, 2003;Eggesbø, 2012;Koivunen et al, 2012), rhinoscleroma (Becker et al, 1981;Pontual et al, 2008), rhinosporidiosis (Bonifaz et al, 2011), sarcoidosis (Manchester, 1994;Mrówka-Kata et al, 2010), systemic mycosis (Zargari and Elpern, 2009;Bonifaz et al, 2011), treponematosis (Hackett, 1976;Manchester, 1994;Aufderheide and Rodríguez-Martín, 1998;Cook, 2002;Ortner, 2003;Cook andPowell, 2005, 2012), tuberculosis (lupus vulgaris) (Manchester, 1994;Ortner, 2003Ortner, , 2008aRoberts and Buikstra, 2003;Garg et al, 2010), and Wegener's granulomatosis (Chauhan and Cruz, 2007). It must be noted, however, that according to Manchester (1994: 80), in what concerns the interpretation of rhinomaxillary lesions only leprosy, tuberculosis (lupus vulgaris) and treponematosis "are of practical significance in paleopathological differential diagnoses.…”

Section: Discussionmentioning

confidence: 99%

Leprosy in individuals unearthed near the Ermida de Santo André and Leprosarium of Beja, Portugal

Antunes‐Ferreira

Matos

Santos

2013

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Documentary sources refer to leprosy patients in the Portuguese territory since the first century AD, and in the Middle Ages around 70 leprosaria were established. However, prior to 2003 this historical evidence had not been confirmed by archeological findings. The excavation performed in monitoring the rehabilitation done by the Polis program in the area of the Ermida de Santo André (hermitage of Saint Andrew) allowed the exhumation of seven human skeletons, and commingled bones from at least three individuals, in the vicinity of the Beja leprosarium. The objective of this study is to present the paleopathological lesions relevant to the discussion of the differential diagnosis of leprosy. Macroscopic observation of the bones and scrutiny of lesions according to the paleopathological literature allowed the identification of a probable case of leprosy in an adult male, showing rhinomaxillary changes and concentric remodeling of hand and foot bones, and four possible cases (two young adults and two adults, all probably males), with a set of lesions in facial bones and skeletal extremities. The poor preservation of the bones precluded further confirmation of this diagnosis. According to historical data, the leprosaria functioned between the 14th and 16th centuries AD. The exact chronology of these findings was not determined either during the excavation or by radiocarbon dating because the bones presented poor collagen levels. In Portugal as a whole there are few osteological evidences of leprosy, and thus this study adds new information about this chronic infectious disease.

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“…Myers et al [2] reported of nasal obstruction (34%), expansile mass (29.0%), epistaxis (23.0%) and epiphora (11.0%). Koivunen et al [11] also reported of nasal obstruction (25.0%), epistaxis (18.0%) and palpable tumor (12.0%) whereas Fasunla and Lasisi [8] reported of nasal obstruction and discharge (100%), cheek swelling (92.7%), cheek pain and paraesthesia (69.5%) and toothache (56.5%). This really indicates that patients who present with nasal blockage, epistaxis, nasal mass and others might be possible candidates of sinonasal tumors.…”

Section: Ent Updatesmentioning

confidence: 99%

“…[10] Koivunen et al reported nasal obstruction (35%), epistaxis (18%) and observable or palpable tumor (12%) in the cases studied. [11] Fasunla and Lasisi found epistaxis, obstruction and nasal discharge in all cases (100%), check swelling (92.7%), cheek pain and paraethesia (69.5%) and toothache (56.5%). [8] In another study by Waldron et al, the most common presenting symptoms were pain (59%), oral symptoms (40%), facial swelling (38%), nasal obstruction (35%) and epistaxis (25%).…”

mentioning

confidence: 99%

Clinical and histopathological presentations of sinonasal cancers in Komfo Anokye Teaching Hospital

Opoku-Buabeng¹

2016

ENT Updates

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A national series of 244 sinonasal cancers in Finland in 1990–2004

Cited by 34 publications

References 17 publications

Paranasal sinuses malignancies: A 12-year review of clinical characteristics

Paranasal sinuses malignancies: A 12-year review of clinical characteristics

Leprosy in individuals unearthed near the Ermida de Santo André and Leprosarium of Beja, Portugal

Clinical and histopathological presentations of sinonasal cancers in Komfo Anokye Teaching Hospital

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