A narrative review on the impact of sarcopenic obesity and its psychological consequence in quality of life

Landscape and research trends of sarcopenic obesity research: A bibliometric analysis

“…The reported prevalence of SO varies widely according to different study population, definitions, and cut-off values [ 4 ]. A number of evidences have showed that SO was associated with increased risk of adverse health-related outcomes, including disability [ 6 ], functional impairment [ 27 ], comorbidities [ 28 , 29 ], mortality [ 7 , 30 ], hospitalization [ 6 ], and reduced quality of life [ 8 ]. Moreover, SO in patients with chronic diseases or cancer were emerging research hotspots.…”

“…Hirani et al [ 6 ] found that men with SO had an increased risk of frailty (OR = 2.00, 95%CI = 1.42–2.82), activities of daily living disability (OR = 1.58, 95%CI = 1.12–2.24), and instrumental activities of daily living disability (OR = 1.36, 95%CI = 1.05–1.76). Studies have shown that SO individuals had a 55.0 % increase in mortality risk compared with non-sarcopenic, non-obese individuals over a follow-up period of 6 years [ 7 ], negatively impacting the quality of life of older adults [ 8 ].…”

Association between Weight-Adjusted Waist Index and Depression in NAFLD: The Modulating Roles of Sex and BMI

“…A prospective cohort study conducted from the China Health and Retirement Longitudinal Study demonstrated that the cumulative burden of WWI was positively associated with the risk of developing depression and was independent of BMI [43]. Sarcopenic obesity is suggested to represent a better association with depression than obesity de ned with BMI [44,45]. A Mendelian randomization analysis demonstrated that low muscle mass was independently associated with risk of depression, even after adjusting for BMI, suggesting that sarcopenia may be the real cause of the increased risk of depression [46].…”