Abstract:Surface and secreted mycobacterial proteins play a major role on the infection process by mediating macrophage-bacteria interactions as well as the fate of cell’s death. We have previously described a secreted 13-kDa lectin (sMTL-13) in Mycobacterium tuberculosis (Mtb), encoded by Rv1419 gene, and although a possible importance for this protein as a major mycobacterial antigen was shown in tuberculosis patients, the importance of such lectin during infection has not been formally addressed. We have generated a… Show more
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