A multivariate blood metabolite algorithm stably predicts risk and resilience to major depressive disorder in the general population

Is resilience a unifying concept for the biological sciences?

“…For example, some studies of metabolic resilience use receiver operator characteristics (ROC) curves and compare recovery using the area under the curve (AUC). 84 , 85 We note, however, that although ROC/AUC gives a measure of fit to a model and allows model comparisons (possible baseline vs. possibly recovered state), it (a) does not include variance in defining a baseline, and (b) there is no resolution to the question of “how close do the AUC values have to be to define a system as having ‘returned’ to baseline?” But this is a promising concept.…”